Decreased Positive Fecal Occult Blood Tests and Delayed Medical Presentation for Colorectal Cancer during the Initial COVID-19 Pandemic Period: A Single-center Experience

• Published in: Journal of the Anus, Rectum and Colon Rectum and Colon, 2024/07/25, Vol.8(3), pp.188-194
• Main Authors: Takagi, Tadataka, Koyama, Fumikazu, Kuge, Hiroyuki, Iwasa, Yosuke, Takei, Takeshi, Sadamitsu, Tomomi, Fujimoto, Kosuke, Harada, Suzuka, Tamura, Takashi, Ejiri, Goki, Yoshikawa, Chihiro, Sho, Masayuki
• Format: Article
• Language: English
• Subjects: colorectal cancer; COVID-19; delayed presentation; fecal occult blood test; Original
• ISSN: 2432-3853; 2432-3853
• DOI: 10.23922/jarc.2023-034

Objectives: This study aimed to investigate the impact of the COVID-19 pandemic on the examination and treatment of colorectal cancer (CRC) and on the behaviors of patients and practitioners.Methods: This is a retrospective analysis of the CRC patients who presented to our department between April 2019 and March 2021 and underwent surgery. Clinical presentation of CRC and time from symptom onset to medical presentation were compared between the control (April 2019 to March 2020, n=124) and COVID-19 pandemic periods (April 2020 to March 2021, n=111).Results: Two hundred and thirty-five patients were reviewed. The rate of positive fecal occult blood tests was significantly lower during the COVID-19 pandemic period (13.5 vs. 25.0%, P = 0.027). Among the symptomatic patients who had melena and abdominal symptoms, the time from symptom onset to medical presentation was significantly longer during the COVID-19 period (115 vs. 31 days, P < 0.001). In addition, the interval between presenting to a practitioner and being referred to our department was similar between the two periods (19 vs. 13 days, P = 0.092). There were no significant differences in the stage of cancer between the two periods. The rate of preoperative sub-obstruction was significantly higher during the COVID-19 period (41.4 vs 23.4%, P = 0.003). There was no significant difference in overall survival and recurrence-free survival between two periods.Conclusions: Hesitation to seek examination and treatment for CRC was observed in patients but not in practitioners during the COVID-19 pandemic period. The prognosis did not change.