Inflammatory myofibroblastic tumor

Inflammatory myofibroblastic tumor is an uncommon lesion of unknown cause. It encompasses a spectrum of myofibroblastic proliferation along with varying amount of inflammatory infiltrate. A number of terms have been applied to the lesion, namely, inflammatory pseudotumor, fibrous xanthoma, plasma ce...

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Bibliographic Details
Published in:Contemporary clinical dentistry 2011-10, Vol.2 (4), p.274-277
Main Authors: Palaskar, Sangeeta, Koshti, Supriya, Maralingannavar, Mahesh, Bartake, Anirudha
Format: Article
Language:English
Subjects:
ALK-1
Autoimmune diseases
Care and treatment
Case studies
Cell proliferation
Cells
Diagnosis
Genetic aspects
Head and neck tumors
Histology
Kinases
Lymphoma
Medical research
myofibroblasts
neoplastic
Original
Physiological aspects
reactive
Tumors
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Description
Summary:Inflammatory myofibroblastic tumor is an uncommon lesion of unknown cause. It encompasses a spectrum of myofibroblastic proliferation along with varying amount of inflammatory infiltrate. A number of terms have been applied to the lesion, namely, inflammatory pseudotumor, fibrous xanthoma, plasma cell granuloma, pseudosarcoma, lymphoid hamartoma, myxoid hamartoma, inflammatory myofibrohistiocytic proliferation, benign myofibroblatoma, and most recently, inflammatory myofibroblastic tumor. The diverse nomenclature is mostly descriptive and reflects the uncertainty regarding true biologic nature of these lesions. Recently, the concept of this lesion being reactive has been challenged based on the clinical demonstration of recurrences and metastasis and cytogenetic evidence of acquired clonal chromosomal abnormalities. We hereby report a case of inflammatory pseudotumor and review its inflammatory versus neoplastic behavior.
ISSN:0976-237X
0976-2361
DOI:10.4103/0976-237X.91787