Clinical review of COVID-19 patients presenting to a quaternary care private hospital in South India: A retrospective study

• Published in: Clinical epidemiology and global health 2021-07, Vol.11, p.100751-100751, Article 100751
• Main Authors: Mohandas, Prithvi, Periasamy, Sathya, Marappan, Manimaran, Sampath, Arun, Garfin Sundaram, Vanaja Kate, Cherian, Vijit Koshy
• Format: Article
• Language: English
• Subjects: COVID-19; Epidemiology; Original; Risk factors; SARS-CoV-2; South India
• ISSN: 2213-3984; 2452-0918; 2213-3984
• DOI: 10.1016/j.cegh.2021.100751

Coronavirus disease 2019 (COVID-19) has been declared a global public-health crisis due to its impact on health, economy, and mental well-being. Here, we evaluated the clinical and epidemiological parameters associated with COVID-19 in South India. A retrospective, quaternary care hospital-based study that included COVID-19 positive patients admitted to MIOT International Hospital, Chennai between 8 April–7 August 2020. Cases were identified by reverse transcriptase-polymerase chain reaction. Epidemiological, demographic, clinical, and radiological findings were recorded and analyzed. The primary endpoint was stable discharge from hospital/patient recovery or death. Associations between risk factors and comorbidities were analyzed using Chi-Square/Fisher's exact test. Of the 5264 cases reviewed, 3345 cases were included. The mean (standard deviation, SD) age of the patients was 47.58 (16.69) years with a median and range hospital stay of 5 (2–41) days. 69.20% of patients were male. The most frequent comorbidities were diabetes (37.10%) and hypertension (29.10%). Contact history was available for 58% of patients. The most common symptoms were cough (36.60%), fever (28.30%), and myalgia (15.40%). Abnormal chest radiography was reported in 16.9% of patients. Phase of admission, age ≥50 years, hypertension, diabetes, coronary artery disease, chronic kidney disease was significantly associated with mortality (p