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Reversal of Jaundice in Two Patients with Inoperable Cholangiocarcinoma Treated with Cisplatin and Gemcitabine Combination

Two patients are presented with severe jaundice, due to inoperable cholangiocarcinoma. The chemotherapeutic approach in patients with severe jaundice is discussed. Many schedules of chemotherapy were developed in this tumor type with normal serum bilirubin. We report here the first successful use of...

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Bibliographic Details
Published in:Case reports in hepatology 2012-01, Vol.2012 (2012), p.1-3
Main Authors: Ponette, Siegfried, Criel, Maarten, Ponette, Johan, Bulte, Katrien, Geurs, Filip
Format: Article
Language:English
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Summary:Two patients are presented with severe jaundice, due to inoperable cholangiocarcinoma. The chemotherapeutic approach in patients with severe jaundice is discussed. Many schedules of chemotherapy were developed in this tumor type with normal serum bilirubin. We report here the first successful use of cisplatin and gemcitabine combination chemotherapy in these patients. Tolerability was good and liver function tests gradually improved.
ISSN:2090-6587
2090-6595
DOI:10.1155/2012/138381