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Detection of microwave radiation of cytochrome CYP102 A1 solution during the enzyme reaction
Microwave radiation at 3.4-4.2 GHz frequency of the cytochrome P450 CYP102 A1 (BM3) solution was registered during the lauric acid hydroxylation reaction. The microwave radiation generation was shown to occur following the addition of electron donor NADPH to a system containing an enzyme and a subst...
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| Published in: | Biochemistry and biophysics reports 2016-03, Vol.5 (C), p.285-289 |
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| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c3863-f8e393d33d3adb458ceec040668c087a87d822f4f80f98e2277bcc0164ed3ee53 |
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| cites | cdi_FETCH-LOGICAL-c3863-f8e393d33d3adb458ceec040668c087a87d822f4f80f98e2277bcc0164ed3ee53 |
| container_end_page | 289 |
| container_issue | C |
| container_start_page | 285 |
| container_title | Biochemistry and biophysics reports |
| container_volume | 5 |
| creator | Ivanov, Yu D Malsagova, K A Izotov, A A Pleshakova, T O Tatur, V Yu Vesnin, S G Ivanova, N D Usanov, S A Archakov, A I |
| description | Microwave radiation at 3.4-4.2 GHz frequency of the cytochrome P450 CYP102 A1 (BM3) solution was registered during the lauric acid hydroxylation reaction. The microwave radiation generation was shown to occur following the addition of electron donor NADPH to a system containing an enzyme and a substrate. The radiation occurs for the enzyme solutions with enzyme concentrations of 10
and 10
М. The microwave radiation effect elicited by the aqueous enzyme solution was observed for the first time. The results obtained can be used to elaborate a new approach to enzyme systems research, including studying of the mechanism of interaction of a functioning enzyme system with microenvironment. |
| doi_str_mv | 10.1016/j.bbrep.2015.12.013 |
| format | article |
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and 10
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and 10
М. The microwave radiation effect elicited by the aqueous enzyme solution was observed for the first time. The results obtained can be used to elaborate a new approach to enzyme systems research, including studying of the mechanism of interaction of a functioning enzyme system with microenvironment.</description><subject>Cytochrome P450</subject><subject>Microwave radiation</subject><subject>Monooxygenase system</subject><issn>2405-5808</issn><issn>2405-5808</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNpVkd9rFDEQx4MottT-BYLsoy-3Tn7tZV-EclYtFPRBHwQhZJPJXY7dzZnsVs6_3txdW1oYyDD5zmeG-RLylkJNgTYftnXXJdzVDKisKauB8hfknAmQC6lAvXySn5HLnLcARcmUZM1rcsZUK6Xi8pz8_oQT2inEsYq-GoJN8a-5wyoZF8xD2e6naDcpDlitfn2nwKorWuXYz0eBm1MY19W0wQrHf_siSmiOyDfklTd9xsv794L8_Hz9Y_V1cfvty83q6nZhuWr4wivkLXe8hHGdkMoiWhDQNMqCWhq1dIoxL7wC3ypkbLnsrC1XEOg4ouQX5ObEddFs9S6FwaS9jiboYyGmtTZpCrZHDUwYbpR3UljhAVrFhLKCWQoNb5UtrI8n1m7uBnQWxymZ_hn0-c8YNnod77RsADhnBfD-HpDinxnzpIeQLfa9GTHOWdNWCMEbQQ9785O0XD3nhP5xDAV9sFlv9dFmfbBZU6aLzaXr3dMNH3seTOX_AW8YpP0</recordid><startdate>20160301</startdate><enddate>20160301</enddate><creator>Ivanov, Yu D</creator><creator>Malsagova, K A</creator><creator>Izotov, A A</creator><creator>Pleshakova, T O</creator><creator>Tatur, V Yu</creator><creator>Vesnin, S G</creator><creator>Ivanova, N D</creator><creator>Usanov, S A</creator><creator>Archakov, A I</creator><general>Elsevier</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20160301</creationdate><title>Detection of microwave radiation of cytochrome CYP102 A1 solution during the enzyme reaction</title><author>Ivanov, Yu D ; Malsagova, K A ; Izotov, A A ; Pleshakova, T O ; Tatur, V Yu ; Vesnin, S G ; Ivanova, N D ; Usanov, S A ; Archakov, A I</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3863-f8e393d33d3adb458ceec040668c087a87d822f4f80f98e2277bcc0164ed3ee53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Cytochrome P450</topic><topic>Microwave radiation</topic><topic>Monooxygenase system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ivanov, Yu D</creatorcontrib><creatorcontrib>Malsagova, K A</creatorcontrib><creatorcontrib>Izotov, A A</creatorcontrib><creatorcontrib>Pleshakova, T O</creatorcontrib><creatorcontrib>Tatur, V Yu</creatorcontrib><creatorcontrib>Vesnin, S G</creatorcontrib><creatorcontrib>Ivanova, N D</creatorcontrib><creatorcontrib>Usanov, S A</creatorcontrib><creatorcontrib>Archakov, A I</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Biochemistry and biophysics reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ivanov, Yu D</au><au>Malsagova, K A</au><au>Izotov, A A</au><au>Pleshakova, T O</au><au>Tatur, V Yu</au><au>Vesnin, S G</au><au>Ivanova, N D</au><au>Usanov, S A</au><au>Archakov, A I</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Detection of microwave radiation of cytochrome CYP102 A1 solution during the enzyme reaction</atitle><jtitle>Biochemistry and biophysics reports</jtitle><addtitle>Biochem Biophys Rep</addtitle><date>2016-03-01</date><risdate>2016</risdate><volume>5</volume><issue>C</issue><spage>285</spage><epage>289</epage><pages>285-289</pages><issn>2405-5808</issn><eissn>2405-5808</eissn><abstract>Microwave radiation at 3.4-4.2 GHz frequency of the cytochrome P450 CYP102 A1 (BM3) solution was registered during the lauric acid hydroxylation reaction. The microwave radiation generation was shown to occur following the addition of electron donor NADPH to a system containing an enzyme and a substrate. The radiation occurs for the enzyme solutions with enzyme concentrations of 10
and 10
М. The microwave radiation effect elicited by the aqueous enzyme solution was observed for the first time. The results obtained can be used to elaborate a new approach to enzyme systems research, including studying of the mechanism of interaction of a functioning enzyme system with microenvironment.</abstract><cop>Netherlands</cop><pub>Elsevier</pub><pmid>28955835</pmid><doi>10.1016/j.bbrep.2015.12.013</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2405-5808 |
| ispartof | Biochemistry and biophysics reports, 2016-03, Vol.5 (C), p.285-289 |
| issn | 2405-5808 2405-5808 |
| language | eng |
| recordid | cdi_doaj_primary_oai_doaj_org_article_024a3a8fd54c4f0098248c42c106398c |
| source | Open Access: PubMed Central; Elsevier ScienceDirect Journals |
| subjects | Cytochrome P450 Microwave radiation Monooxygenase system |
| title | Detection of microwave radiation of cytochrome CYP102 A1 solution during the enzyme reaction |
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