Extraction of bioactive compounds from Psidium guajava and their application in dentistry

Guava is considered as poor man’s apple rich in phytochemicals with medicinal value and hence it is highly consumed. Gas chromatography–mass spectroscopy (GC–MS) analysis of guava leaf extract revealed the presence of various bioactive compounds with antimicrobial, antioxidant, anticancer, and antit...

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Bibliographic Details
Published in:AMB Express 2019-12, Vol.9 (1), p.208-9, Article 208
Main Authors: Shaheena, Shaik, Chintagunta, Anjani Devi, Dirisala, Vijaya Ramu, Sampath Kumar, N. S.
Format: Article
Language:English
Subjects:
Abrasive cleaning
Abrasiveness
Anticancer properties
Antiinfectives and antibacterials
Antimicrobial activity
Antimicrobial agents
Antioxidants
Bioactive compounds
Biocompatibility
Biological activity
Biomedical and Life Sciences
Biotechnology
Chemical activity
Cleansing ability
Coconut oil
Cytotoxicity
Dentistry
Essential oils
Foaming
Formulation
Formulations
Gas chromatography
Guava
Herbal toothpaste
Ingredients
Life Sciences
Mass spectroscopy
Microbial Genetics and Genomics
Microbiology
Oral hygiene
Organic chemistry
Original
Original Article
Peppermint
Peppermint oil
Plant extracts
Toothpaste
Toxicity
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Summary:Guava is considered as poor man’s apple rich in phytochemicals with medicinal value and hence it is highly consumed. Gas chromatography–mass spectroscopy (GC–MS) analysis of guava leaf extract revealed the presence of various bioactive compounds with antimicrobial, antioxidant, anticancer, and antitumor properties. Hence, it is used in tooth paste formulations along with other ingredients such as Acacia arabica gum powder, stevia herb powder, sea salt, extra virgin coconut oil, peppermint oil in the present study. Three formulations F1, F2 and F3 have been made by varying the concentration of these ingredients and the prepared formulations were studied for their antimicrobial activity and physico-chemical parameters such as pH, abrasiveness, foaming activity, spreading and cleaning ability. Among these, F3 showed significant antioxidant and antimicrobial properties, minimal cytotoxicity, maximum spreadability and very high cleaning ability. This study surmises that the herbal toothpaste formulation is greener, rich in medicinal values and imparts oral hygiene.
ISSN:2191-0855
2191-0855
DOI:10.1186/s13568-019-0935-x