Molecular Responses to the Zika Virus in Mosquitoes

The Zika virus (ZIKV), originally discovered in 1947, did not become a major concern until the virus swept across the Pacific and into the Americas in the last decade, bringing with it news of neurological complications and birth defects in ZIKV affected areas. This prompted researchers to dissect t...

Full description

Saved in:
Bibliographic Details
Published in:Pathogens (Basel) 2018-05, Vol.7 (2), p.49
Main Authors: Alfonso-Parra, Catalina, Avila, Frank W
Format: Article
Language:English
Subjects:
Aedes aegypti
Aedes albopictus
Aquatic insects
Birth defects
Congenital defects
Dengue fever
Flavivirus
Infections
Microbiota
Microcephaly
Molecular interactions
Mosquitoes
Neurological complications
Outbreaks
Parasites
Researchers
Review
Vector-borne diseases
Viruses
Zika virus
ZIKV
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The Zika virus (ZIKV), originally discovered in 1947, did not become a major concern until the virus swept across the Pacific and into the Americas in the last decade, bringing with it news of neurological complications and birth defects in ZIKV affected areas. This prompted researchers to dissect the molecular interactions between ZIKV and the mosquito vector in an attempt to better understand not only the changes that occur upon infection, but to also identify molecules that may potentially enhance or suppress a mosquito's ability to become infected and/or transmit the virus. Here, we review what is currently known regarding ZIKV-mosquito molecular interactions, focusing on ZIKV infection of and , the primary species implicated in transmitting ZIKV during the recent outbreaks.
ISSN:2076-0817
2076-0817
DOI:10.3390/pathogens7020049