Increasing Malaria Parasite Clearance Time after Chloroquine Therapy, South Korea, 2000-2016

We reviewed the clinical efficacy of chloroquine for Plasmodium vivax malaria, the changing trend of parasite clearance time, and fever clearance time during 2000-2016 in South Korea. Median parasite clearance time and fever clearance time increased significantly over the study period. Chloroquine w...

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Bibliographic Details
Published in:Emerging infectious diseases 2020-08, Vol.26 (8), p.1852-1855
Main Authors: Park, Seong Yeon, Park, Yoon Soo, Park, Yoonseon, Kwak, Yee Gyung, Song, Je Eun, Lee, Kkot Sil, Cho, Shin-Hyeong, Lee, Sang-Eun, Shin, Hyun-Il, Yeom, Joon-Sup
Format: Article
Language:English
Subjects:
Chloroquine
Disease control
Dispatch
Drug dosages
Drug resistance
Fever
fever clearance time
hydroxychloroquine
Increasing Malaria Parasite Clearance Time after Chloroquine Therapy, South Korea, 2000–2016
Malaria
Military personnel
parasite clearance time
Parasites
Patients
Plasmodium falciparum
Plasmodium vivax
Primaquine
Soldiers
Systematic review
Trends
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Summary:We reviewed the clinical efficacy of chloroquine for Plasmodium vivax malaria, the changing trend of parasite clearance time, and fever clearance time during 2000-2016 in South Korea. Median parasite clearance time and fever clearance time increased significantly over the study period. Chloroquine was mostly underdosed when used to treat P. vivax malaria.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid2608.190687