Prediction of Deterioration of Left Ventricular Function Using 3-Dimensional Speckle-Tracking Echocardiography in Patients With Left Bundle-Branch Block

• Published in: Journal of the American Heart Association 2023-01, Vol.12 (1), p.e026194-e026194
• Main Authors: Kim, Hyue Mee, Hwang, In-Chang, Yoon, Yeonyee Elizabeth, Park, Jun-Bean, Lee, Seung-Pyo, Kim, Hyung-Kwan, Kim, Yong-Jin, Lim, Yaeji, Cho, Goo-Yeong
• Format: Article
• Language: English
• Subjects: 3D echocardiography; Bundle-Branch Block; Echocardiography - methods; Echocardiography, Three-Dimensional - methods; Humans; left bundle‐branch block; Original Research; Retrospective Studies; speckle‐tracking echocardiography; Stroke Volume; Ventricular Dysfunction, Left - diagnostic imaging; Ventricular Dysfunction, Left - etiology; Ventricular Function, Left
• ISSN: 2047-9980; 2047-9980
• DOI: 10.1161/JAHA.122.026194

Background Previous studies have demonstrated that 2-dimensional (2D) global longitudinal strain (GLS) is associated with cardiovascular outcomes in patients with left bundle-branch block. However, the predictive value of 3-dimensional (3D) speckle-tracking echocardiography has not yet been investigated in these patients. Methods and Results The authors retrospectively identified 290 patients with left bundle-branch block who underwent echocardiography more than twice. Using speckle-tracking echocardiography, 2D-GLS, 3D-GLS, 3D-global circumferential strain, 3D global radial strain, and 3D global area strain were acquired. The association between 2D and 3D strains and the follow-up left ventricular (LV) ejection fraction (LVEF) was analyzed. The study population was divided into 2 sets: a group with preserved LVEF (baseline LVEF ≥40%) and a group with reduced LVEF (baseline LVEF