Agarose Gel Characterization for the Fabrication of Brain Tissue Phantoms for Infrared Multispectral Vision Systems

Synthetic phantoms that recreate the characteristics of biological tissues are valuable tools for systematically studying and comprehending physiologies, pathologies, and biological processes related to tissues. The reproduction of mechanical and optical properties allows for the development and eva...

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Bibliographic Details
Published in:Gels 2023-11, Vol.9 (12), p.944
Main Authors: Albor-Ramírez, Efraín, Reyes-Alberto, Miguel, Vidal-Flores, Luis M, Gutierrez-Herrera, Enoch, Padilla-Castañeda, Miguel A
Format: Article
Language:English
Subjects:
Accuracy
agarose
Biological activity
Brain
Brain research
Calibration
Hemodynamics
Hemoglobin
Hydrogels
Infrared imaging
Light
Medical imaging
Medical personnel
Milk
multispectral imaging
near infrared vision
Optical properties
phantom
Polyvinyl alcohol
Spectrum analysis
tissue-like phantom
Tissues
Tomography
Vision systems
Visualization
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Summary:Synthetic phantoms that recreate the characteristics of biological tissues are valuable tools for systematically studying and comprehending physiologies, pathologies, and biological processes related to tissues. The reproduction of mechanical and optical properties allows for the development and evaluation of novel systems and applications in areas such as imaging, optics, ultrasound, or dosimetry, among others. This paper proposes a methodology for manufacturing agarose-based phantoms that mimics the optical properties of healthy brain tissue within the wavelength infrared range of 800 to 820 nm. The fabrication of such phantoms enables the possibility of testing and experimentation in controlled and safe environments toward the design of new near-infrared multispectral imaging systems in neurosurgery. The results of an experimental optical characterization study indicate the validity and reliability of the proposed method for fabricating brain tissue phantoms in a cost-effective and straightforward fashion.
ISSN:2310-2861
2310-2861
DOI:10.3390/gels9120944