Simple convergent-nozzle aerosol injector for single-particle diffractive imaging with X-ray free-electron lasers

A major challenge in high-resolution x-ray free-electron laser-based coherent diffractive imaging is the development of aerosol injectors that can efficiently deliver particles to the peak intensity of the focused X-ray beam. Here, we consider the use of a simple convergent-orifice nozzle for produc...

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Bibliographic Details
Published in:Structural dynamics (Melville, N.Y.) N.Y.), 2015-07, Vol.2 (4), p.041717-041717
Main Authors: Kirian, R A, Awel, S, Eckerskorn, N, Fleckenstein, H, Wiedorn, M, Adriano, L, Bajt, S, Barthelmess, M, Bean, R, Beyerlein, K R, Chavas, L M G, Domaracky, M, Heymann, M, Horke, D A, Knoska, J, Metz, M, Morgan, A, Oberthuer, D, Roth, N, Sato, T, Xavier, P L, Yefanov, O, Rode, A V, Küpper, J, Chapman, H N
Format: Article
Language:English
Subjects:
Aerosols
Atmospheric pressure
Convergence
Efficiency
Experiments
Free electron lasers
Injectors
Ion beams
Laser applications
Microscopy
Nanoparticles
Nozzles
Orifices
Particle beams
SPECIAL TOPIC: BIOLOGY WITH X-RAY LASERS 2
X ray imagery
X-rays
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Summary:A major challenge in high-resolution x-ray free-electron laser-based coherent diffractive imaging is the development of aerosol injectors that can efficiently deliver particles to the peak intensity of the focused X-ray beam. Here, we consider the use of a simple convergent-orifice nozzle for producing tightly focused beams of particles. Through optical imaging we show that 0.5 μm particles can be focused to a full-width at half maximum diameter of 4.2 μm, and we demonstrate the use of such a nozzle for injecting viruses into a micro-focused soft-X-ray FEL beam.
ISSN:2329-7778
2329-7778
DOI:10.1063/1.4922648