The Impact of Cognitive Behavioral Therapy for Insomnia on Sleep Log and Actigraphy Outcomes in People with Multiple Sclerosis: A Secondary Analysis

• Published in: Nature and science of sleep 2021-01, Vol.13, p.1865-1874
• Main Authors: Williams-Cooke, Cierra, LeSuer, Leslie, Drerup, Michelle, Siengsukon, Catherine
• Format: Article
• Language: English
• Subjects: actigraphy; Analysis; Anxiety; Behavior modification; Behavioral health care; Care and treatment; Cognitive behavioral therapy; cognitive behavioral therapy for insomnia; Cognitive therapy; Data collection; Fatigue; Insomnia; Multiple sclerosis; Original Research; Quality standards; Questionnaires; Sleep; sleep log
• ISSN: 1179-1608; 1179-1608
• DOI: 10.2147/NSS.S324879

While studies indicate cognitive behavioral therapy for insomnia (CBT-I) improves self-report sleep outcomes from questionnaires in people with multiple sclerosis (MS), it is unclear if CBT-I improves outcomes from a sleep log or sleep assessed objectively via actigraphy in people with MS. This study aimed to determine if CBT-I improves sleep log and actigraphy outcomes in individuals with MS. Twenty-five participants ( = 53.04, = 10.90) were included in this secondary analysis of data from a pilot randomized control study to assess the feasibility and treatment effect of CBT-I in individuals with MS. Participants were asked to maintain a sleep log and wear an actigraph for a week at baseline and post-intervention. Participants were randomized into one of three groups (CBT-I, active control, or one-time brief education control group). One-way ANOVAs were used to assess for group differences and within group change in sleep latency, sleep efficiency (SE), time in bed, total sleep time (TST), wake after sleep onset, variability of SE, and variability of TST. CBT-I resulted in an increase in sleep efficiency (SE) and decrease in time in bed (TIB) and variability of SE from the sleep log. The CBT-I group also experienced a decrease in TIB and total sleep time (TST) from actigraphy. The active control group demonstrated an increase in variability of SE from actigraphy. This study indicates that individuals with MS may experience an improvement in sleep log and actigraphy sleep outcomes following CBT-I, but findings need to be replicated in a larger prospective study. The decrease in TST from actigraphy mirrors results from prior studies.