A case of refractory onychomycosis caused by Kloeckera apiculata: Successful treatment with itraconazole

Here, we present the case of an otherwise healthy patient, without risk factors, who developed a refractory case of onychomycosis caused by Kloeckera apiculata, an uncommon human pathogen. The diagnosis was ultimately confirmed by fungal nail plate culture, histopathology, and PCR. Whereas prior tre...

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Bibliographic Details
Published in:Medical mycology case reports 2024-12, Vol.46, p.100669, Article 100669
Main Authors: Ehrlich-Fein, Samantha S., Patel, Samir B.
Format: Article
Language:English
Subjects:
Case Report
Dermatology
Itraconzaole
Kloeckera apiculata
Nail disease
Onychomycosis
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Summary:Here, we present the case of an otherwise healthy patient, without risk factors, who developed a refractory case of onychomycosis caused by Kloeckera apiculata, an uncommon human pathogen. The diagnosis was ultimately confirmed by fungal nail plate culture, histopathology, and PCR. Whereas prior treatments with topical 5 % tavaborole solution, oral terbinafine, and oral fluconazole were ineffective, complete clinical and mycological cure was achieved with a 3-month course of oral itraconazole.
ISSN:2211-7539
2211-7539
DOI:10.1016/j.mmcr.2024.100669