Pathological fractures of distal tibia and fibula with a parathyroid adenoma: A rare case report and review of literature

Primary hyperparathyroidism may mimic osteoporosis and lead to pathological fractures. We report a case of 35-year-old female who sustained left distal tibia-fibula fracture after a trivial fall, later diagnosed to have left inferior parathyroid adenoma. The fracture was managed conservatively and l...

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Bibliographic Details
Published in:Journal of Orthopaedic Reports 2022-09, Vol.1 (3), p.100051, Article 100051
Main Authors: Srinivasan, Smruti, Rai, Abhishek Kumar, Thomson, Caroline, Naidu, Ajay
Format: Article
Language:English
Subjects:
Parathyroid adenoma
Parathyroidectomy
Pathological fracture
SPECT
Tibia-fibula fracture
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Summary:Primary hyperparathyroidism may mimic osteoporosis and lead to pathological fractures. We report a case of 35-year-old female who sustained left distal tibia-fibula fracture after a trivial fall, later diagnosed to have left inferior parathyroid adenoma. The fracture was managed conservatively and left inferior parathyroidectomy for the adenoma. At four years follow-up, there are no clinical or biochemical signs of recurrence. Pathological fracture in a case of parathyroid adenoma is extremely rare and require a multidisciplinary approach for optimal outcome. A combination of clinical, biological, radiological and biochemical markers with a high index of suspicion in an isolated bone fracture is required to diagnose parathyroid adenoma.
ISSN:2773-157X
2773-157X
DOI:10.1016/j.jorep.2022.100051