A review of adverse cutaneous drug reactions resulting from the use of interferon and ribavirin

Drug-induced cutaneous eruptions are named among the most common side effects of many medications. Thus, cutaneous drug eruptions are a common cause of morbidity and mortality, especially in hospital settings. The present article reviews different presentations of drug-induced cutaneous eruptions, w...

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Bibliographic Details
Published in:Canadian journal of gastroenterology 2009-10, Vol.23 (10), p.677-683
Main Authors: Mistry, Nisha, Shapero, Jonathan, Crawford, Richard I
Format: Article
Language:English
Subjects:
Alopecia - chemically induced
Antiviral Agents - adverse effects
Drug Eruptions - etiology
Drug Therapy, Combination
Eczema - chemically induced
Hepatitis C - drug therapy
Humans
Interferons - adverse effects
Psoriasis - chemically induced
Review
Ribavirin - adverse effects
Sarcoidosis - chemically induced
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Summary:Drug-induced cutaneous eruptions are named among the most common side effects of many medications. Thus, cutaneous drug eruptions are a common cause of morbidity and mortality, especially in hospital settings. The present article reviews different presentations of drug-induced cutaneous eruptions, with a focus on eruptions reported secondary to the use of interferon and ribavirin. Presentations include injection site reactions, psoriasis, eczematous drug reactions, alopecia, sarcoidosis, lupus, fixed drug eruptions, pigmentary changes and lichenoid eruptions. Also reviewed are findings regarding life-threatening systemic drug reactions.
ISSN:0835-7900
DOI:10.1155/2009/651952