Healthy-related quality of life in patients with cervical cancer in Southwest China: a cross-sectional study

• Published in: BMC health services research 2021-08, Vol.21 (1), p.841-841, Article 841
• Main Authors: Zhao, Min, Luo, Lei, zhang, Chun-hong, zhang, Jin-ping, Yuan, Jia-yan, Gu, Rong-yan, Ding, Song-rui
• Format: Article
• Language: English
• Subjects: Care and treatment; Cervical cancer; Diagnosis; FACT-cx (4.0); Health aspects; Health-related quality of life; Influencing factors; Prognosis; Quality of life
• ISSN: 1472-6963; 1472-6963
• DOI: 10.1186/s12913-021-06723-7

Background Cervical cancer is the second most common female malignant tumor in the world. According to a study in 2018, the incidence of cervical cancer in Yunnan Province of China was 11.42 per 100,000, the mortality rate was 3.77 per 100,000, and higher than the national average. Health-related quality of life (HRQoL) can be used not only in the selection and effect evaluation of clinical treatment plans of cervical cancer, but also in the evaluation of prognosis and long-term survival status. In this study, 288 cervical cancer patients admitted to the Yunnan Cancer Hospital in Southwest China from 2018 to 2020 were used as the survey objects to understand the HRQoL of cervical cancer patients and explore the related factors that affect HRQoL. Methods The Chinese version of the functional assessment of cancer therapy-cervix (functional assessment of cancer therapy-cervix v4.0, FACT-Cx V4) was used to investigate 288 patients with cervical cancer in Yunnan Province. Statistical analysis was performed using t-test, analysis of variance, multiple linear regression and other methods. Results The total FACT-Cx score of cervical cancer patients was (130.16 [+ or -] 14.20), the physical well-being (PWB) score was (22.02 [+ or -] 4.47), the social/family well-being (SWB) score was (25.66 [+ or -] 3.59), the emotional well-being (EWB) score was (19.75 [+ or -] 3.54), the functional well-being (FWB) score was (16.91 [+ or -] 5.01) and the additional focus area (cervical cancer subscale, CxS) score was (45.78 [+ or -] 4.61). From the multi-factor analysis results, the scores of PWB, FWB, Cxs and the total FACT-Cx were related to the choice of different treatment methods, the PWB scores of patients with concurrent chemoradiotherapy was low([beta] = - 1.67, P = 0.003), the FWB scores of patients with concurrent chemoradiotherapy was low([beta] = - 2.02, P = 0.001), the CxS scores of patients with concurrent chemoradiotherapy was low([beta] = - 1.61, P = 0.006), the total score of FACT-Cx of patients with concurrent chemoradiotherapy was low([beta] = - 5.91, P = 0.001). SWB score was affected by marital status, married patients had high PWB scores([beta] = 5.44, P = 0.006). The patients with heavy disease expenditures as aproportion of family disposable income([beta] = - 3.82, P = 0.002) and aged 60 and above([beta] = - 3.29, P = 0.003) had lower FWB scores. The total score FACT-Cx of patients participating in cervical cancer screening was higher([beta] = 7.61, P = 0.