COVID-19 Treatment Guidelines: Do They Really Reflect Best Medical Practices to Manage the Pandemic?

SARS-CoV-2 (COVID-19) has been changing the world since December 2019. A comprehensive search into many COVID-19 treatment guidelines was conducted and reported in this article. This is a review paper to probe differences in COVID-19 managing strategies and explore the most common treatment plans am...

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Bibliographic Details
Published in:Infectious disease reports 2021-04, Vol.13 (2), p.259-284
Main Authors: Jirjees, Feras, Saad, Ali K, Al Hano, Zahraa, Hatahet, Taher, Al Obaidi, Hala, Dallal Bashi, Yahya H
Format: Article
Language:English
Subjects:
Antibiotics
Antiviral agents
Availability
Clinical trials
Coronaviruses
Corticoids
Corticosteroids
COVID-19
COVID-19 treatment guidelines
Disease
Drug dosages
Ebola virus
FDA approval
Guidelines
Health care facilities
Health services
Hospitalization
Immunotherapy
Infections
Influenza
medications
Middle East respiratory syndrome
Mortality
Pandemics
Pediatrics
pharmacological management
Respiratory diseases
Review
Severe acute respiratory syndrome coronavirus 2
therapeutics guidelines
Viruses
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Summary:SARS-CoV-2 (COVID-19) has been changing the world since December 2019. A comprehensive search into many COVID-19 treatment guidelines was conducted and reported in this article. This is a review paper to probe differences in COVID-19 managing strategies and explore the most common treatment plans among countries. Published guidelines from 23 countries and three references guidelines—until the end of 2020—were included in this article. The majority of COVID-19 treatment options were reported in this review and it includes antiviral drugs, antimalarial drugs, antibiotics, corticosteroids, immunotherapy, anticoagulants, and other pharmacological treatment. The presence of such information from different countries in a single comprehensive review article could help in understanding and speculation of variation in the recommended treatment in each country. This might be related to the cost of medications, the access to the medications, availability of medication that could potentially be useful in managing COVID-19 cases, and the availability/capacity of healthcare facilities. Finally, although there are various treatment groups listed in the published therapeutic guidelines worldwide, unfortunately, there is no evidence for effectiveness of most of these medications in reducing the COVID-19 mortality curve over more than one year of this global pandemic.
ISSN:2036-7449
2036-7430
2036-7449
DOI:10.3390/idr13020029