Loading…
Effectiveness of confidential reports to physicians on their prescribing of antipsychotic medications in nursing homes
Antipsychotic medication use in nursing homes is associated with potential for harms. In Ontario, Canada, an agency of the provincial government offers nursing home physicians quarterly audit and feedback on their antipsychotic prescribing. We compared the characteristics of physicians who did and d...
Saved in:
Published in: | Implementation science communications 2020-02, Vol.1 (1), p.30-14, Article 30 |
---|---|
Main Authors: | , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | cdi_FETCH-LOGICAL-c563t-11ec6d4b59b86bbf7bb8e54da3192992a3f52d3620220384edae6e3e3b8588c33 |
---|---|
cites | cdi_FETCH-LOGICAL-c563t-11ec6d4b59b86bbf7bb8e54da3192992a3f52d3620220384edae6e3e3b8588c33 |
container_end_page | 14 |
container_issue | 1 |
container_start_page | 30 |
container_title | Implementation science communications |
container_volume | 1 |
creator | Ivers, Noah M Taljaard, Monica Giannakeas, Vasily Reis, Catherine Mulhall, Cara L Lam, Jonathan M C Burchell, Ann N Lebovic, Gerald Bronskill, Susan E |
description | Antipsychotic medication use in nursing homes is associated with potential for harms. In Ontario, Canada, an agency of the provincial government offers nursing home physicians quarterly audit and feedback on their antipsychotic prescribing. We compared the characteristics of physicians who did and did not engage with the intervention, and assessed early changes in prescribing.
This population-level, retrospective cohort study used linked administrative databases to track prescribing practices in nursing homes pre-intervention (baseline), immediately post-initiative (3 months), and at follow-up (6 months). Exposure variables identified whether a physician signed up to participate (or not) or viewed the feedback following sign up (or not). Differences in the proportion of days that residents received antipsychotic medications at 6 months compared to baseline by exposure(s) were assessed using a linear mixed effects regression analysis to adjust for a range of resident, physician, and nursing home factors. Benzodiazepine and statin prescribing were assessed as a balance and tracer measures, respectively.
Of 944 eligible physicians, 210 (22.3%) signed up to recieve the feedback report and 132 (13.9%) viewed their feedback. Physicians who signed up for feedback were more likely to have graduated from a Canadian medical school, work in urban nursing homes, and care for a larger number of residents. The clinical and functional characteristics of residents were similar across physician exposure groups. At 6 months, antipsychotic prescribing had decreased in all exposure groups. Those who viewed their feedback report had a signicantly greater reduction in antipsychotic prescribing than those who did not sign up (0.94% patient-days exposed; 95% CI 0.35 to 1.54%,
= 0.002). Trends in prescribing patterns across exposure groups for benzodiazepines and statins were not statistically significant.
Almost a quarter of eligible physicians engaged early in a voluntary audit and feedback intervention related to antipsychotic prescribing in nursing homes. Those who viewed their feedback achieved a small but statistically significant change in prescribing, equivalent to approximately 14,000 fewer days that nursing home residents received antipsychotic medications over 6 months. This study adds to the literature regarding the role of audit and feedback interventions to improve quality of care. |
doi_str_mv | 10.1186/s43058-020-00013-9 |
format | article |
fullrecord | <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_0483dea7ee204f2d9b35cbf46f43439a</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_0483dea7ee204f2d9b35cbf46f43439a</doaj_id><sourcerecordid>2546848180</sourcerecordid><originalsourceid>FETCH-LOGICAL-c563t-11ec6d4b59b86bbf7bb8e54da3192992a3f52d3620220384edae6e3e3b8588c33</originalsourceid><addsrcrecordid>eNpdkk9r3DAQxU1paUKaL9BDMfTSi1v9t3QplJA2gUAv7VlI8mitxSu5kr2w3z7abBKSniQ0v_eYGb2m-YjRV4yl-FYYRVx2iKAOIYRpp94050QI0hGC8dsX97PmspRthQjHmCH2vjmjREqOpTpv9tfeg1vCHiKU0ibfuhR9GCAuwUxthjnlpbRLaufxUIILJlYqtssIIbdzhuJysCFujlJTRXM5uDEtwbU7GIIzS0hVEWIb11yO3Jh2UD4077yZClw-nhfN35_Xf65uurvfv26vftx1jgu6dBiDEwOzXFkprPW9tRI4GwzFiihFDPWcDFQQRAiiksFgQAAFaiWX0lF60dyefIdktnrOYWfyQScT9MNDyhttcm12Ao2YpAOYHoAg5smgLOXOeiY8o4wqU72-n7zm1dbZXF1RNtMr09eVGEa9SXvdM9IrJKvBl0eDnP6tUBa9C8XBNJkIaS2asPo7PemxqOjn_9BtWnOsq9KEMyGZxBJVipwol1MpGfxzMxjpY0r0KSW6pkQ_pESrKvr0coxnyVMm6D3pFrq3</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2546848180</pqid></control><display><type>article</type><title>Effectiveness of confidential reports to physicians on their prescribing of antipsychotic medications in nursing homes</title><source>Publicly Available Content Database</source><source>PubMed Central(OpenAccess)</source><creator>Ivers, Noah M ; Taljaard, Monica ; Giannakeas, Vasily ; Reis, Catherine ; Mulhall, Cara L ; Lam, Jonathan M C ; Burchell, Ann N ; Lebovic, Gerald ; Bronskill, Susan E</creator><creatorcontrib>Ivers, Noah M ; Taljaard, Monica ; Giannakeas, Vasily ; Reis, Catherine ; Mulhall, Cara L ; Lam, Jonathan M C ; Burchell, Ann N ; Lebovic, Gerald ; Bronskill, Susan E</creatorcontrib><description>Antipsychotic medication use in nursing homes is associated with potential for harms. In Ontario, Canada, an agency of the provincial government offers nursing home physicians quarterly audit and feedback on their antipsychotic prescribing. We compared the characteristics of physicians who did and did not engage with the intervention, and assessed early changes in prescribing.
This population-level, retrospective cohort study used linked administrative databases to track prescribing practices in nursing homes pre-intervention (baseline), immediately post-initiative (3 months), and at follow-up (6 months). Exposure variables identified whether a physician signed up to participate (or not) or viewed the feedback following sign up (or not). Differences in the proportion of days that residents received antipsychotic medications at 6 months compared to baseline by exposure(s) were assessed using a linear mixed effects regression analysis to adjust for a range of resident, physician, and nursing home factors. Benzodiazepine and statin prescribing were assessed as a balance and tracer measures, respectively.
Of 944 eligible physicians, 210 (22.3%) signed up to recieve the feedback report and 132 (13.9%) viewed their feedback. Physicians who signed up for feedback were more likely to have graduated from a Canadian medical school, work in urban nursing homes, and care for a larger number of residents. The clinical and functional characteristics of residents were similar across physician exposure groups. At 6 months, antipsychotic prescribing had decreased in all exposure groups. Those who viewed their feedback report had a signicantly greater reduction in antipsychotic prescribing than those who did not sign up (0.94% patient-days exposed; 95% CI 0.35 to 1.54%,
= 0.002). Trends in prescribing patterns across exposure groups for benzodiazepines and statins were not statistically significant.
Almost a quarter of eligible physicians engaged early in a voluntary audit and feedback intervention related to antipsychotic prescribing in nursing homes. Those who viewed their feedback achieved a small but statistically significant change in prescribing, equivalent to approximately 14,000 fewer days that nursing home residents received antipsychotic medications over 6 months. This study adds to the literature regarding the role of audit and feedback interventions to improve quality of care.</description><identifier>ISSN: 2662-2211</identifier><identifier>EISSN: 2662-2211</identifier><identifier>DOI: 10.1186/s43058-020-00013-9</identifier><identifier>PMID: 32885189</identifier><language>eng</language><publisher>England: BioMed Central</publisher><subject>Aggressiveness ; Ambulatory care ; Antipsychotic prescribing ; Antipsychotics ; Audit and feedback ; Audits ; Feedback ; Health insurance ; Initiatives ; Interrupted time series ; Long term health care ; Nursing care ; Nursing homes ; Physicians ; Privacy ; Psychotropic drugs</subject><ispartof>Implementation science communications, 2020-02, Vol.1 (1), p.30-14, Article 30</ispartof><rights>The Author(s) 2020.</rights><rights>2020. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.</rights><rights>The Author(s) 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c563t-11ec6d4b59b86bbf7bb8e54da3192992a3f52d3620220384edae6e3e3b8588c33</citedby><cites>FETCH-LOGICAL-c563t-11ec6d4b59b86bbf7bb8e54da3192992a3f52d3620220384edae6e3e3b8588c33</cites><orcidid>0000-0003-2500-2435</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2546848180/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2546848180?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32885189$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ivers, Noah M</creatorcontrib><creatorcontrib>Taljaard, Monica</creatorcontrib><creatorcontrib>Giannakeas, Vasily</creatorcontrib><creatorcontrib>Reis, Catherine</creatorcontrib><creatorcontrib>Mulhall, Cara L</creatorcontrib><creatorcontrib>Lam, Jonathan M C</creatorcontrib><creatorcontrib>Burchell, Ann N</creatorcontrib><creatorcontrib>Lebovic, Gerald</creatorcontrib><creatorcontrib>Bronskill, Susan E</creatorcontrib><title>Effectiveness of confidential reports to physicians on their prescribing of antipsychotic medications in nursing homes</title><title>Implementation science communications</title><addtitle>Implement Sci Commun</addtitle><description>Antipsychotic medication use in nursing homes is associated with potential for harms. In Ontario, Canada, an agency of the provincial government offers nursing home physicians quarterly audit and feedback on their antipsychotic prescribing. We compared the characteristics of physicians who did and did not engage with the intervention, and assessed early changes in prescribing.
This population-level, retrospective cohort study used linked administrative databases to track prescribing practices in nursing homes pre-intervention (baseline), immediately post-initiative (3 months), and at follow-up (6 months). Exposure variables identified whether a physician signed up to participate (or not) or viewed the feedback following sign up (or not). Differences in the proportion of days that residents received antipsychotic medications at 6 months compared to baseline by exposure(s) were assessed using a linear mixed effects regression analysis to adjust for a range of resident, physician, and nursing home factors. Benzodiazepine and statin prescribing were assessed as a balance and tracer measures, respectively.
Of 944 eligible physicians, 210 (22.3%) signed up to recieve the feedback report and 132 (13.9%) viewed their feedback. Physicians who signed up for feedback were more likely to have graduated from a Canadian medical school, work in urban nursing homes, and care for a larger number of residents. The clinical and functional characteristics of residents were similar across physician exposure groups. At 6 months, antipsychotic prescribing had decreased in all exposure groups. Those who viewed their feedback report had a signicantly greater reduction in antipsychotic prescribing than those who did not sign up (0.94% patient-days exposed; 95% CI 0.35 to 1.54%,
= 0.002). Trends in prescribing patterns across exposure groups for benzodiazepines and statins were not statistically significant.
Almost a quarter of eligible physicians engaged early in a voluntary audit and feedback intervention related to antipsychotic prescribing in nursing homes. Those who viewed their feedback achieved a small but statistically significant change in prescribing, equivalent to approximately 14,000 fewer days that nursing home residents received antipsychotic medications over 6 months. This study adds to the literature regarding the role of audit and feedback interventions to improve quality of care.</description><subject>Aggressiveness</subject><subject>Ambulatory care</subject><subject>Antipsychotic prescribing</subject><subject>Antipsychotics</subject><subject>Audit and feedback</subject><subject>Audits</subject><subject>Feedback</subject><subject>Health insurance</subject><subject>Initiatives</subject><subject>Interrupted time series</subject><subject>Long term health care</subject><subject>Nursing care</subject><subject>Nursing homes</subject><subject>Physicians</subject><subject>Privacy</subject><subject>Psychotropic drugs</subject><issn>2662-2211</issn><issn>2662-2211</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNpdkk9r3DAQxU1paUKaL9BDMfTSi1v9t3QplJA2gUAv7VlI8mitxSu5kr2w3z7abBKSniQ0v_eYGb2m-YjRV4yl-FYYRVx2iKAOIYRpp94050QI0hGC8dsX97PmspRthQjHmCH2vjmjREqOpTpv9tfeg1vCHiKU0ibfuhR9GCAuwUxthjnlpbRLaufxUIILJlYqtssIIbdzhuJysCFujlJTRXM5uDEtwbU7GIIzS0hVEWIb11yO3Jh2UD4077yZClw-nhfN35_Xf65uurvfv26vftx1jgu6dBiDEwOzXFkprPW9tRI4GwzFiihFDPWcDFQQRAiiksFgQAAFaiWX0lF60dyefIdktnrOYWfyQScT9MNDyhttcm12Ao2YpAOYHoAg5smgLOXOeiY8o4wqU72-n7zm1dbZXF1RNtMr09eVGEa9SXvdM9IrJKvBl0eDnP6tUBa9C8XBNJkIaS2asPo7PemxqOjn_9BtWnOsq9KEMyGZxBJVipwol1MpGfxzMxjpY0r0KSW6pkQ_pESrKvr0coxnyVMm6D3pFrq3</recordid><startdate>20200225</startdate><enddate>20200225</enddate><creator>Ivers, Noah M</creator><creator>Taljaard, Monica</creator><creator>Giannakeas, Vasily</creator><creator>Reis, Catherine</creator><creator>Mulhall, Cara L</creator><creator>Lam, Jonathan M C</creator><creator>Burchell, Ann N</creator><creator>Lebovic, Gerald</creator><creator>Bronskill, Susan E</creator><general>BioMed Central</general><general>BMC</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-2500-2435</orcidid></search><sort><creationdate>20200225</creationdate><title>Effectiveness of confidential reports to physicians on their prescribing of antipsychotic medications in nursing homes</title><author>Ivers, Noah M ; Taljaard, Monica ; Giannakeas, Vasily ; Reis, Catherine ; Mulhall, Cara L ; Lam, Jonathan M C ; Burchell, Ann N ; Lebovic, Gerald ; Bronskill, Susan E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c563t-11ec6d4b59b86bbf7bb8e54da3192992a3f52d3620220384edae6e3e3b8588c33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Aggressiveness</topic><topic>Ambulatory care</topic><topic>Antipsychotic prescribing</topic><topic>Antipsychotics</topic><topic>Audit and feedback</topic><topic>Audits</topic><topic>Feedback</topic><topic>Health insurance</topic><topic>Initiatives</topic><topic>Interrupted time series</topic><topic>Long term health care</topic><topic>Nursing care</topic><topic>Nursing homes</topic><topic>Physicians</topic><topic>Privacy</topic><topic>Psychotropic drugs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ivers, Noah M</creatorcontrib><creatorcontrib>Taljaard, Monica</creatorcontrib><creatorcontrib>Giannakeas, Vasily</creatorcontrib><creatorcontrib>Reis, Catherine</creatorcontrib><creatorcontrib>Mulhall, Cara L</creatorcontrib><creatorcontrib>Lam, Jonathan M C</creatorcontrib><creatorcontrib>Burchell, Ann N</creatorcontrib><creatorcontrib>Lebovic, Gerald</creatorcontrib><creatorcontrib>Bronskill, Susan E</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Implementation science communications</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ivers, Noah M</au><au>Taljaard, Monica</au><au>Giannakeas, Vasily</au><au>Reis, Catherine</au><au>Mulhall, Cara L</au><au>Lam, Jonathan M C</au><au>Burchell, Ann N</au><au>Lebovic, Gerald</au><au>Bronskill, Susan E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effectiveness of confidential reports to physicians on their prescribing of antipsychotic medications in nursing homes</atitle><jtitle>Implementation science communications</jtitle><addtitle>Implement Sci Commun</addtitle><date>2020-02-25</date><risdate>2020</risdate><volume>1</volume><issue>1</issue><spage>30</spage><epage>14</epage><pages>30-14</pages><artnum>30</artnum><issn>2662-2211</issn><eissn>2662-2211</eissn><abstract>Antipsychotic medication use in nursing homes is associated with potential for harms. In Ontario, Canada, an agency of the provincial government offers nursing home physicians quarterly audit and feedback on their antipsychotic prescribing. We compared the characteristics of physicians who did and did not engage with the intervention, and assessed early changes in prescribing.
This population-level, retrospective cohort study used linked administrative databases to track prescribing practices in nursing homes pre-intervention (baseline), immediately post-initiative (3 months), and at follow-up (6 months). Exposure variables identified whether a physician signed up to participate (or not) or viewed the feedback following sign up (or not). Differences in the proportion of days that residents received antipsychotic medications at 6 months compared to baseline by exposure(s) were assessed using a linear mixed effects regression analysis to adjust for a range of resident, physician, and nursing home factors. Benzodiazepine and statin prescribing were assessed as a balance and tracer measures, respectively.
Of 944 eligible physicians, 210 (22.3%) signed up to recieve the feedback report and 132 (13.9%) viewed their feedback. Physicians who signed up for feedback were more likely to have graduated from a Canadian medical school, work in urban nursing homes, and care for a larger number of residents. The clinical and functional characteristics of residents were similar across physician exposure groups. At 6 months, antipsychotic prescribing had decreased in all exposure groups. Those who viewed their feedback report had a signicantly greater reduction in antipsychotic prescribing than those who did not sign up (0.94% patient-days exposed; 95% CI 0.35 to 1.54%,
= 0.002). Trends in prescribing patterns across exposure groups for benzodiazepines and statins were not statistically significant.
Almost a quarter of eligible physicians engaged early in a voluntary audit and feedback intervention related to antipsychotic prescribing in nursing homes. Those who viewed their feedback achieved a small but statistically significant change in prescribing, equivalent to approximately 14,000 fewer days that nursing home residents received antipsychotic medications over 6 months. This study adds to the literature regarding the role of audit and feedback interventions to improve quality of care.</abstract><cop>England</cop><pub>BioMed Central</pub><pmid>32885189</pmid><doi>10.1186/s43058-020-00013-9</doi><tpages>14</tpages><orcidid>https://orcid.org/0000-0003-2500-2435</orcidid><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 2662-2211 |
ispartof | Implementation science communications, 2020-02, Vol.1 (1), p.30-14, Article 30 |
issn | 2662-2211 2662-2211 |
language | eng |
recordid | cdi_doaj_primary_oai_doaj_org_article_0483dea7ee204f2d9b35cbf46f43439a |
source | Publicly Available Content Database; PubMed Central(OpenAccess) |
subjects | Aggressiveness Ambulatory care Antipsychotic prescribing Antipsychotics Audit and feedback Audits Feedback Health insurance Initiatives Interrupted time series Long term health care Nursing care Nursing homes Physicians Privacy Psychotropic drugs |
title | Effectiveness of confidential reports to physicians on their prescribing of antipsychotic medications in nursing homes |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T07%3A09%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effectiveness%20of%20confidential%20reports%20to%20physicians%20on%20their%20prescribing%20of%20antipsychotic%20medications%20in%20nursing%20homes&rft.jtitle=Implementation%20science%20communications&rft.au=Ivers,%20Noah%20M&rft.date=2020-02-25&rft.volume=1&rft.issue=1&rft.spage=30&rft.epage=14&rft.pages=30-14&rft.artnum=30&rft.issn=2662-2211&rft.eissn=2662-2211&rft_id=info:doi/10.1186/s43058-020-00013-9&rft_dat=%3Cproquest_doaj_%3E2546848180%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c563t-11ec6d4b59b86bbf7bb8e54da3192992a3f52d3620220384edae6e3e3b8588c33%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2546848180&rft_id=info:pmid/32885189&rfr_iscdi=true |