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Inequalities in excess premature mortality in England during the COVID-19 pandemic: a cross-sectional analysis of cumulative excess mortality by area deprivation and ethnicity
ObjectivesTo examine magnitude of the impact of the COVID-19 pandemic on inequalities in premature mortality in England by deprivation and ethnicity.DesignA statistical model to estimate increased mortality in population subgroups during the COVID-19 pandemic by comparing observed with expected mort...
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Published in: | BMJ open 2021-12, Vol.11 (12), p.e052646-e052646 |
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description | ObjectivesTo examine magnitude of the impact of the COVID-19 pandemic on inequalities in premature mortality in England by deprivation and ethnicity.DesignA statistical model to estimate increased mortality in population subgroups during the COVID-19 pandemic by comparing observed with expected mortality in each group based on trends over the previous 5 years.SettingInformation on deaths registered in England since 2015 was used, including age, sex, area of residence and cause of death. Ethnicity was obtained from Hospital Episode Statistics records linked to death data.ParticipantsPopulation study of England, including all 569 824 deaths from all causes registered between 21 March 2020 and 26 February 2021.Main outcome measuresExcess mortality in each subgroup over and above the number expected based on trends in mortality in that group over the previous 5 years.ResultsThe gradient in excess mortality by area deprivation was greater in the under 75s (the most deprived areas had 1.25 times as many deaths as expected, least deprived 1.14) than in all ages (most deprived had 1.24 times as many deaths as expected, least deprived 1.20). Among the black and Asian groups, all area deprivation quintiles had significantly larger excesses than white groups in the most deprived quintiles and there were no clear gradients across quintiles. Among the white group, only those in the most deprived quintile had more excess deaths than deaths directly involving COVID-19.ConclusionThe COVID-19 pandemic has widened inequalities in premature mortality by area deprivation. Among those under 75, the direct and indirect effects of the pandemic on deaths have disproportionately impacted ethnic minority groups irrespective of area deprivation, and the white group the most deprived areas. Statistics limited to deaths directly involving COVID-19 understate the pandemic’s impact on inequalities by area deprivation and ethnic group at younger ages. |
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Ethnicity was obtained from Hospital Episode Statistics records linked to death data.ParticipantsPopulation study of England, including all 569 824 deaths from all causes registered between 21 March 2020 and 26 February 2021.Main outcome measuresExcess mortality in each subgroup over and above the number expected based on trends in mortality in that group over the previous 5 years.ResultsThe gradient in excess mortality by area deprivation was greater in the under 75s (the most deprived areas had 1.25 times as many deaths as expected, least deprived 1.14) than in all ages (most deprived had 1.24 times as many deaths as expected, least deprived 1.20). Among the black and Asian groups, all area deprivation quintiles had significantly larger excesses than white groups in the most deprived quintiles and there were no clear gradients across quintiles. Among the white group, only those in the most deprived quintile had more excess deaths than deaths directly involving COVID-19.ConclusionThe COVID-19 pandemic has widened inequalities in premature mortality by area deprivation. Among those under 75, the direct and indirect effects of the pandemic on deaths have disproportionately impacted ethnic minority groups irrespective of area deprivation, and the white group the most deprived areas. Statistics limited to deaths directly involving COVID-19 understate the pandemic’s impact on inequalities by area deprivation and ethnic group at younger ages.</description><identifier>ISSN: 2044-6055</identifier><identifier>EISSN: 2044-6055</identifier><identifier>DOI: 10.1136/bmjopen-2021-052646</identifier><identifier>PMID: 34949618</identifier><language>eng</language><publisher>England: British Medical Journal Publishing Group</publisher><subject>Age ; Coronaviruses ; COVID-19 ; Cross-Sectional Studies ; England - epidemiology ; epidemiology ; Estimates ; Ethnic and Racial Minorities ; Ethnicity ; Humans ; Minority & ethnic groups ; Minority Groups ; Mortality ; Mortality, Premature ; Pandemics ; Premature mortality ; Public Health ; SARS-CoV-2 ; Trends</subject><ispartof>BMJ open, 2021-12, Vol.11 (12), p.e052646-e052646</ispartof><rights>Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2022 Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b539t-1d64126fe7e7e0a51aa321fc383d1201485f6e1ca6b7f8ed31f493e6fb38c89f3</citedby><cites>FETCH-LOGICAL-b539t-1d64126fe7e7e0a51aa321fc383d1201485f6e1ca6b7f8ed31f493e6fb38c89f3</cites><orcidid>0000-0001-7582-5558 ; 0000-0003-0491-2077</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2613056169/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2613056169?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,3194,25753,27924,27925,37012,37013,38516,43895,44590,53791,53793,55341,55350,74412,75126,77596,77597,77660,77686</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34949618$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Barnard, Sharmani</creatorcontrib><creatorcontrib>Fryers, Paul</creatorcontrib><creatorcontrib>Fitzpatrick, Justine</creatorcontrib><creatorcontrib>Fox, Sebastian</creatorcontrib><creatorcontrib>Waller, Zachary</creatorcontrib><creatorcontrib>Baker, Allan</creatorcontrib><creatorcontrib>Burton, Paul</creatorcontrib><creatorcontrib>Newton, John</creatorcontrib><creatorcontrib>Doyle, Yvonne</creatorcontrib><creatorcontrib>Goldblatt, Peter</creatorcontrib><title>Inequalities in excess premature mortality in England during the COVID-19 pandemic: a cross-sectional analysis of cumulative excess mortality by area deprivation and ethnicity</title><title>BMJ open</title><addtitle>BMJ Open</addtitle><addtitle>BMJ Open</addtitle><description>ObjectivesTo examine magnitude of the impact of the COVID-19 pandemic on inequalities in premature mortality in England by deprivation and ethnicity.DesignA statistical model to estimate increased mortality in population subgroups during the COVID-19 pandemic by comparing observed with expected mortality in each group based on trends over the previous 5 years.SettingInformation on deaths registered in England since 2015 was used, including age, sex, area of residence and cause of death. Ethnicity was obtained from Hospital Episode Statistics records linked to death data.ParticipantsPopulation study of England, including all 569 824 deaths from all causes registered between 21 March 2020 and 26 February 2021.Main outcome measuresExcess mortality in each subgroup over and above the number expected based on trends in mortality in that group over the previous 5 years.ResultsThe gradient in excess mortality by area deprivation was greater in the under 75s (the most deprived areas had 1.25 times as many deaths as expected, least deprived 1.14) than in all ages (most deprived had 1.24 times as many deaths as expected, least deprived 1.20). Among the black and Asian groups, all area deprivation quintiles had significantly larger excesses than white groups in the most deprived quintiles and there were no clear gradients across quintiles. Among the white group, only those in the most deprived quintile had more excess deaths than deaths directly involving COVID-19.ConclusionThe COVID-19 pandemic has widened inequalities in premature mortality by area deprivation. Among those under 75, the direct and indirect effects of the pandemic on deaths have disproportionately impacted ethnic minority groups irrespective of area deprivation, and the white group the most deprived areas. Statistics limited to deaths directly involving COVID-19 understate the pandemic’s impact on inequalities by area deprivation and ethnic group at younger ages.</description><subject>Age</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Cross-Sectional Studies</subject><subject>England - epidemiology</subject><subject>epidemiology</subject><subject>Estimates</subject><subject>Ethnic and Racial Minorities</subject><subject>Ethnicity</subject><subject>Humans</subject><subject>Minority & ethnic groups</subject><subject>Minority Groups</subject><subject>Mortality</subject><subject>Mortality, Premature</subject><subject>Pandemics</subject><subject>Premature mortality</subject><subject>Public Health</subject><subject>SARS-CoV-2</subject><subject>Trends</subject><issn>2044-6055</issn><issn>2044-6055</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><sourceid>COVID</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp9UstuEzEUHSEQrUq_AAlZYsNmWr8zZoGEQimRKnUDbC2P5zpxNDNO7Zmo-Sp-EU-SvlhgS7ble865176nKN4TfEEIk5d1tw4b6EuKKSmxoJLLV8UpxZyXEgvx-tn5pDhPaY3z4EIJQd8WJ4wrriSpTos_ix7uRtP6wUNCvkdwbyEltInQmWGMgLoQhym-m6JX_bI1fYOaMfp-iYYVoPnt78W3kii0yQHovP2MDLIxpFQmsIMPvWmRycsu-YSCQ3bsxtYMfgsPyZ5S1DtkIhjUwCb6rZnYaMoHw6r3NiPeFW-caROcH_ez4tf3q5_zH-XN7fVi_vWmrAVTQ0kayQmVDmZ5YiOIMYwSZ1nFGkIx4ZVwEog1sp65ChpGHFcMpKtZZSvl2FmxOOg2wax1LqYzcaeD8Xp_EeJSmzh424LGXDkgTgEQzplrlFPEUsmwtLappclaXw5am7HuoLHQD9G0L0RfRnq_0suw1dWMYClYFvh0FIjhboQ06M4nC21uBYQxaSoJpxwzgjP04z_QdRhj_v09imEhiVQZxQ6ofZ8iuMdiCNaTv_TRX3rylz74K7M-PH_HI-fBTRlweQBk9lPe_0n-BQ2Y4NM</recordid><startdate>20211201</startdate><enddate>20211201</enddate><creator>Barnard, Sharmani</creator><creator>Fryers, Paul</creator><creator>Fitzpatrick, Justine</creator><creator>Fox, Sebastian</creator><creator>Waller, Zachary</creator><creator>Baker, Allan</creator><creator>Burton, Paul</creator><creator>Newton, John</creator><creator>Doyle, Yvonne</creator><creator>Goldblatt, Peter</creator><general>British Medical Journal Publishing Group</general><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0001-7582-5558</orcidid><orcidid>https://orcid.org/0000-0003-0491-2077</orcidid></search><sort><creationdate>20211201</creationdate><title>Inequalities in excess premature mortality in England during the COVID-19 pandemic: a cross-sectional analysis of cumulative excess mortality by area deprivation and ethnicity</title><author>Barnard, Sharmani ; Fryers, Paul ; Fitzpatrick, Justine ; Fox, Sebastian ; Waller, Zachary ; Baker, Allan ; Burton, Paul ; Newton, John ; Doyle, Yvonne ; Goldblatt, Peter</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b539t-1d64126fe7e7e0a51aa321fc383d1201485f6e1ca6b7f8ed31f493e6fb38c89f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Age</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>Cross-Sectional Studies</topic><topic>England - epidemiology</topic><topic>epidemiology</topic><topic>Estimates</topic><topic>Ethnic and Racial Minorities</topic><topic>Ethnicity</topic><topic>Humans</topic><topic>Minority & ethnic groups</topic><topic>Minority Groups</topic><topic>Mortality</topic><topic>Mortality, Premature</topic><topic>Pandemics</topic><topic>Premature mortality</topic><topic>Public Health</topic><topic>SARS-CoV-2</topic><topic>Trends</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barnard, Sharmani</creatorcontrib><creatorcontrib>Fryers, Paul</creatorcontrib><creatorcontrib>Fitzpatrick, Justine</creatorcontrib><creatorcontrib>Fox, Sebastian</creatorcontrib><creatorcontrib>Waller, Zachary</creatorcontrib><creatorcontrib>Baker, Allan</creatorcontrib><creatorcontrib>Burton, Paul</creatorcontrib><creatorcontrib>Newton, John</creatorcontrib><creatorcontrib>Doyle, Yvonne</creatorcontrib><creatorcontrib>Goldblatt, Peter</creatorcontrib><collection>BMJ Open Access Journals</collection><collection>BMJ Journals:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Coronavirus Research Database</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Psychology Database (ProQuest)</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>BMJ open</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Barnard, Sharmani</au><au>Fryers, Paul</au><au>Fitzpatrick, Justine</au><au>Fox, Sebastian</au><au>Waller, Zachary</au><au>Baker, Allan</au><au>Burton, Paul</au><au>Newton, John</au><au>Doyle, Yvonne</au><au>Goldblatt, Peter</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Inequalities in excess premature mortality in England during the COVID-19 pandemic: a cross-sectional analysis of cumulative excess mortality by area deprivation and ethnicity</atitle><jtitle>BMJ open</jtitle><stitle>BMJ Open</stitle><addtitle>BMJ Open</addtitle><date>2021-12-01</date><risdate>2021</risdate><volume>11</volume><issue>12</issue><spage>e052646</spage><epage>e052646</epage><pages>e052646-e052646</pages><issn>2044-6055</issn><eissn>2044-6055</eissn><abstract>ObjectivesTo examine magnitude of the impact of the COVID-19 pandemic on inequalities in premature mortality in England by deprivation and ethnicity.DesignA statistical model to estimate increased mortality in population subgroups during the COVID-19 pandemic by comparing observed with expected mortality in each group based on trends over the previous 5 years.SettingInformation on deaths registered in England since 2015 was used, including age, sex, area of residence and cause of death. Ethnicity was obtained from Hospital Episode Statistics records linked to death data.ParticipantsPopulation study of England, including all 569 824 deaths from all causes registered between 21 March 2020 and 26 February 2021.Main outcome measuresExcess mortality in each subgroup over and above the number expected based on trends in mortality in that group over the previous 5 years.ResultsThe gradient in excess mortality by area deprivation was greater in the under 75s (the most deprived areas had 1.25 times as many deaths as expected, least deprived 1.14) than in all ages (most deprived had 1.24 times as many deaths as expected, least deprived 1.20). Among the black and Asian groups, all area deprivation quintiles had significantly larger excesses than white groups in the most deprived quintiles and there were no clear gradients across quintiles. Among the white group, only those in the most deprived quintile had more excess deaths than deaths directly involving COVID-19.ConclusionThe COVID-19 pandemic has widened inequalities in premature mortality by area deprivation. Among those under 75, the direct and indirect effects of the pandemic on deaths have disproportionately impacted ethnic minority groups irrespective of area deprivation, and the white group the most deprived areas. Statistics limited to deaths directly involving COVID-19 understate the pandemic’s impact on inequalities by area deprivation and ethnic group at younger ages.</abstract><cop>England</cop><pub>British Medical Journal Publishing Group</pub><pmid>34949618</pmid><doi>10.1136/bmjopen-2021-052646</doi><orcidid>https://orcid.org/0000-0001-7582-5558</orcidid><orcidid>https://orcid.org/0000-0003-0491-2077</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Age Coronaviruses COVID-19 Cross-Sectional Studies England - epidemiology epidemiology Estimates Ethnic and Racial Minorities Ethnicity Humans Minority & ethnic groups Minority Groups Mortality Mortality, Premature Pandemics Premature mortality Public Health SARS-CoV-2 Trends |
title | Inequalities in excess premature mortality in England during the COVID-19 pandemic: a cross-sectional analysis of cumulative excess mortality by area deprivation and ethnicity |
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