Recent advances in perioperative blood management

Transfusion of blood and blood products has many adverse effects and should be done only if patient benefits outweigh the associated risks. Current understanding of blood transfusion has improved dramatically, revolutionising the care of surgical, trauma, obstetric and critically ill patients. Most...

Full description

Saved in:
Bibliographic Details
Published in:Indian journal of anaesthesia 2023-01, Vol.67 (1), p.130-138
Main Authors: Krishna, Handattu M, Prasad, Mukesh Kumar, Mitragotri, Milon V, Bipin, G I, Gupta, Divya, Sharma, Ridhima
Format: Article
Language:English
Subjects:
Anemia
Biological products
blood
Blood collection and preservation
blood platelets
Blood products
Blood transfusion
Blood transfusions
Care and treatment
Diagnosis
Evidence-based medicine
Health aspects
Hemoglobin
Measurement
Patient outcomes
Perioperative care
plasma
red blood cells
Special
Tranexamic acid
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Transfusion of blood and blood products has many adverse effects and should be done only if patient benefits outweigh the associated risks. Current understanding of blood transfusion has improved dramatically, revolutionising the care of surgical, trauma, obstetric and critically ill patients. Most guidelines advise a restrictive approach for stable patients with non-haemorrhagic anaemia for red blood cell transfusion. The rationale for red blood cell transfusion has historically been to improve oxygen transport capacity and consumption-related parameters in anaemic patients. Current understanding casts serious doubts about the true potential of red blood cell transfusions to improve these factors. There may not be any benefit from blood transfusion beyond a haemoglobin threshold of 7 g/dL. In fact, liberal transfusion may be associated with higher complications. Guideline-based transfusion policy should be adopted for the administration of all blood products including fresh frozen plasma, platelet concentrates and cryoprecipitate etc. This should be integrated with clinical judgement.
ISSN:0019-5049
0976-2817
DOI:10.4103/ija.ija_1043_22