Characterization of postoperative LASIK ectasia features on higher-order aberration excimer ablation maps

To characterize anterior corneal higher-order aberration (HOA) excimer ablation map patterns in postoperative LASIK ectasia (POE) and to examine correlations between newly identified corneal HOA ablation map features of POE and known topographic indices. Prospective multicenter non-interventional de...

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Published in:BMC ophthalmology 2023-12, Vol.23 (1), p.517-517, Article 517
Main Authors: Wallerstein, Avi, Santhakumaran, Sangeetha, Tabunar, Lauren, Cohen, Mark, Gauvin, Mathieu
Format: Article
Language:English
Subjects:
Ablation
Ablation (Surgery)
Astigmatism
Biomechanics
Contoura
Cornea
Cornea - surgery
Corneal Topography
Corneal Wavefront Aberration - diagnosis
Diagnosis
Dilatation, Pathologic
Ectasia
Higher-order aberration
Humans
Information processing
Islands
Keratomileusis, Laser In Situ - adverse effects
Keratomileusis, Laser In Situ - methods
Lasers
Lasers, Excimer - therapeutic use
Medical diagnosis
Myopia - surgery
Patients
Prospective Studies
Refraction, Ocular
Reproducibility
Software
Surgeons
Topography
Visual Acuity
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creator Wallerstein, Avi
Santhakumaran, Sangeetha
Tabunar, Lauren
Cohen, Mark
Gauvin, Mathieu
description To characterize anterior corneal higher-order aberration (HOA) excimer ablation map patterns in postoperative LASIK ectasia (POE) and to examine correlations between newly identified corneal HOA ablation map features of POE and known topographic indices. Prospective multicenter non-interventional descriptive study. A total of 28 eyes from 22 POE patients were enrolled. The postoperative HOA ablation map was derived from Topolyzer Vario corneal imaging at the time of POE diagnosis. Features that recurred were identified and then analyzed. Correlations to Orbscan indices were studied. An arrangement of two elliptical paracentral ablation islands, deep inferior and shallow superior, in direct mirror-like opposition to each other, were identified on all HOA maps. The paracentral islands were accompanied by peripheral ablation crescents. The deep paracentral inferior island 'hot spot' coincided with the topographical apical POE cone and was highly reproducible in angular position (249.3 ± 17.3°). There was significant variation in ablation depth (shallow superior island: 11.5 ± 6.9 μm and deep inferior island: 32.5 ± 18.8 μm). The superior crescents had high variability in depth (34.8 ± 18.9 μm). Strong correlations were found between the corneal irregularity index and the ablation depth difference between the deep and shallow paracentral islands (R = 0.96; P 
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Strong correlations were found between the corneal irregularity index and the ablation depth difference between the deep and shallow paracentral islands (R = 0.96; P &lt; 0.0001). The corneal HOA excimer ablation map revealed a recurring, distinct, easily recognizable pattern in POE eyes. Validated Orbscan POE indices and HOA ablation map islands showed a strong correlation. It is possible to extract useful information from the corneal HOA ablation map, potentially making it suitable for diagnosing and monitoring POE although more studies are needed.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>38124047</pmid><doi>10.1186/s12886-023-03263-y</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record>
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source Publicly Available Content Database; PubMed Central
subjects Ablation
Ablation (Surgery)
Astigmatism
Biomechanics
Contoura
Cornea
Cornea - surgery
Corneal Topography
Corneal Wavefront Aberration - diagnosis
Diagnosis
Dilatation, Pathologic
Ectasia
Higher-order aberration
Humans
Information processing
Islands
Keratomileusis, Laser In Situ - adverse effects
Keratomileusis, Laser In Situ - methods
Lasers
Lasers, Excimer - therapeutic use
Medical diagnosis
Myopia - surgery
Patients
Prospective Studies
Refraction, Ocular
Reproducibility
Software
Surgeons
Topography
Visual Acuity
title Characterization of postoperative LASIK ectasia features on higher-order aberration excimer ablation maps
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