Endemic Pemphigus foliaceus ("Fogo selvagem"): a series from the Northeastern region of the State of São Paulo, Brazil, 1973-1998

Endemic Pemphigus Foliaceus (EPF) is a bullous autoimmune skin disease whose incidence used to be high in the State of São Paulo (SP), Brazil, during the forties, but has declined thereafter. to report a series of EPF patients from the northeastern region of SP. a retrospective study concerning demo...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo 2001-04, Vol.43 (2), p.59-62
Main Authors: Chiossi, M P, Roselino, A M
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Brazil - epidemiology
Child
Endemic Diseases
Epidemiology
Female
Fogo selvagem
Humans
Male
Middle Aged
Pemphigus
Pemphigus - diagnosis
Pemphigus - epidemiology
Pemphigus foliaceus
Retrospective Studies
TROPICAL MEDICINE
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Summary:Endemic Pemphigus Foliaceus (EPF) is a bullous autoimmune skin disease whose incidence used to be high in the State of São Paulo (SP), Brazil, during the forties, but has declined thereafter. to report a series of EPF patients from the northeastern region of SP. a retrospective study concerning demographic and epidemiological data of patients seen from 1973 to 1998 was conducted at the University Hospital, Faculty of Medicine of Ribeirão Preto, SP. bullous disease was diagnosed in 340 patients, 245 with EPF (72.1%), 9.4 cases per year, 60.4% females, and 70.2% white, 7 to 82 year-old (29.4% in their teens); 46.9% lived in the rural zone. Concerning profession, housewives predominated among women (67.6%) and agricultural workers among men (40.2%). The time of disease was less than 1 year in 62.0% of cases, followed by 1 and 5 years (27%), and more than 5 years for the remaining patients (11%). 36.7% of patients were referred by the Direção Regional de Saúde (DIR) XVIII of Ribeirão Preto, with the largest number of cases being from Ribeirão Preto and Batatais: 33.3% and 23.3%, respectively; 22% from DIR XIII (Franca); 13.5% from DIR VII (Araraquara); 2.9% from DIR IX (Barretos); 4.1% from other DIRs of SP, and 20.8% from other States (16.7% from Minas Gerais). Thirteen (5.3%) patients reported occurrence of the disease in some relative, and 4 (1.6%) in neighbors. the present data characterize the northeastern region of the state of São Paulo as a remaining endemic focus of EPF.
ISSN:0036-4665
1678-9946
0036-4665
1678-9946
DOI:10.1590/s0036-46652001000200001