CANDIDA AURIS: EMERGENCE AND EPIDEMIOLOGY OF A HIGHLY PATHOGENIC YEAST

Candida auris is a multidrug-resistant emerging yeast, which was responsible for healthcare-associated infection outbreaks, and was cataloged as a new species in 2009, after being isolated from a patient’s ear canal secretion in Japan. Since the notification of this first occurrence, numerous cases...

Full description

Saved in:
Bibliographic Details
Published in:Clinical and Biomedical Research 2017-09, Vol.37 (3), p.247-254
Main Authors: Santos, Paula Slomp, Dalla Lana, Daiane Flores, Mezzari, Adelina
Format: Article
Language:English
Subjects:
biofilm
Candida auris
candidemia
candidiasis
diagnosis
epidemiology
multidrug-resistance
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Candida auris is a multidrug-resistant emerging yeast, which was responsible for healthcare-associated infection outbreaks, and was cataloged as a new species in 2009, after being isolated from a patient’s ear canal secretion in Japan. Since the notification of this first occurrence, numerous cases have been reported throughout the world, including Brazil. C. auris affects mainly inpatients, patients in intensive care units, exposed to broad-spectrum antifungal medications and who make use of vascular catheters. Currently, this yeast is one of the main responsible for invasive infections in hospitals and has been cause of concern by authorities and organs due to its rapid dissemination and difficult treatment caused by its low susceptibility to antifungal agents traditionally used in clinical practice. As a contributor to the severity of infections associated with C. auris, the transmission mechanism is still unknown, which implies in a lack of control of the microorganism and high mortality rates. Thus, this literature review presents relevant information in order to alert the importance of C. auris as an etiological agent of systemic infections, as well as its epidemiology and the real challenges of the treatment. Keywords: Candida auris; candidiasis; candidemia; multidrug-resistance; biofilm; epidemiology; diagnosis
ISSN:2357-9730
0101-5575
2357-9730
DOI:10.4322/2357-9730.73982