Severe autogenously fecal peritonitis in Wistar rats with permanent bilateral carotid occlusion. Response to intra peritoneal moxifloxacin combined with dexamethasone

PURPOSE:To evaluate the treatment outcome of severe peritonitis in rats submitted to permanent bilateral carotid occlusion (PBCO).METHODS:Sixteen Wistar rats (mean age of 8.5 months) with PBCO underwent autogenously fecal peritonitis, and were treated with moxifloxacin combined with dexamethasone, a...

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Bibliographic Details
Published in:Acta cirúrgica brasileira 2014-02, Vol.29 (2), p.76-81
Main Authors: Melo, Maria Cecília Santos Cavalcanti, Gadelha, Diego Nery Benevides, Oliveira, Thárcia Kiara Beserra, Brandt, Carlos Teixeira
Format: Article
Language:English
Subjects:
Dexamethasone
Peritonitis
Quinolones
Rats
Therapy
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Summary:PURPOSE:To evaluate the treatment outcome of severe peritonitis in rats submitted to permanent bilateral carotid occlusion (PBCO).METHODS:Sixteen Wistar rats (mean age of 8.5 months) with PBCO underwent autogenously fecal peritonitis, and were treated with moxifloxacin combined with dexamethasone, and followed-up for 45 days. Ten rats (mean age five months) without PBCO were used as a control group. The variables were expressed by their mean and standard error of the mean (SEM). p
ISSN:0102-8650
0102-8650
DOI:10.1590/S0102-86502014000200001