Synthesis, Structural and Biological Properties of the Ring-A Sulfonamido Substituted Chalcones: A Review

Sulfonamidochalcones continue to assert themselves as versatile synthetic intermedi-ates and several articles continue to appear in literature describing their synthesis, chemical transformation and biological properties. These compounds are not only of interest from the medicinal chemistry context,...

Full description

Saved in:
Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2021-09, Vol.26 (19), p.5923
Main Author: Mphahlele, Malose J.
Format: Article
Language:English
Subjects:
Biological activity
Biological properties
Carbon
Chemistry
Chloride
Hydrogen
molecular structure
NMR
Nuclear magnetic resonance
o/m/p-sulfonamidochalcones
Optical materials
Optical properties
Review
Reviews
Single crystals
Sulfonamides
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Sulfonamidochalcones continue to assert themselves as versatile synthetic intermedi-ates and several articles continue to appear in literature describing their synthesis, chemical transformation and biological properties. These compounds are not only of interest from the medicinal chemistry context, their conformations and crystalline structures also continue to attract attention to explore non-covalent (intramolecular and intermolecular) interactions, control molecular conformations, and improve their physicochemical and optical properties. Despite an exhaustive list of examples of the ring-A sulfonamide-appended chalcones described in the literature, there is no com-prehensive review dedicated to their synthesis, structural and biological properties. This review focuses attention on the synthesis, structure and biological properties of the ring-A sulfonamide-appended chalcones (o/m/p-sulfonamidochalcones) as well as their potential as non-linear optical materials.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules26195923