Computed tomography-guided lung biopsy with rapid on-site evaluation for diagnosis of lung lesions: a meta-analysis

• Published in: Journal of cardiothoracic surgery 2023-04, Vol.18 (1), p.122-122, Article 122
• Main Authors: Wu, Di, Liu, Yue-Yue, Wang, Tao, Huang, Ya-Yong, Xia, Ping
• Format: Article
• Language: English
• Subjects: Accuracy; Adequacy; Assessments; Bias; Biopsy; Bronchoscopy; Complications; Computed tomography; CT imaging; Diagnosis; Diagnostic systems; Evaluation; Hemorrhage; Heterogeneity; Humans; Image-Guided Biopsy - adverse effects; Image-Guided Biopsy - methods; Lesions; Lung - diagnostic imaging; Lung - pathology; Lung biopsy; Lung diseases; Lung Diseases - complications; Lung Neoplasms - pathology; Lungs; Meta-analysis; Onsite; Patients; Pneumothorax; Pneumothorax - etiology; Rapid On-site Evaluation; Retrospective Studies; Review; Tomography; Tomography, X-Ray Computed - methods
• ISSN: 1749-8090; 1749-8090
• DOI: 10.1186/s13019-023-02212-6

Lung biopsy (LB) procedures performed with computed tomography (CT guidance can enable the reliable diagnosis of lung lesions. These diagnostic efforts can be further expedited through a rapid on-site evaluation (ROSE) approach, allowing for the rapid assessment of collected tissue samples to gauge the adequacy of these samples, their features, and associated cytomorphological characteristics. The present analysis was developed to examine the safety and efficacy of CT-guided LB with ROSE as a means of diagnosing lung lesions. Studies published as of July 31, 2022 in the PubMed, Embase, and Wanfang databases were identified for this meta-analysis. Diagnostic accuracy was the primary endpoint, while secondary endpoints included the operative duration, the number of punctures, and rates of lung hemorrhage, pneumothorax, and secondary LB. This meta-analysis included 6 total studies. Relative to CT alone, CT with ROSE was associated with a significant increase in diagnostic accuracy (P