Dual-task versus single-task gait rehabilitation after stroke: the protocol of the cognitive-motor synergy multicenter, randomized, controlled superiority trial (SYNCOMOT)

• Published in: Current controlled trials in cardiovascular medicine 2023-03, Vol.24 (1), p.172-16, Article 172
• Main Authors: Tasseel-Ponche, Sophie, Roussel, Martine, Toba, Monica N, Sader, Thibaud, Barbier, Vincent, Delafontaine, Arnaud, Meynier, Jonathan, Picard, Carl, Constans, Jean-Marc, Schnitzler, Alexis, Godefroy, Olivier, Yelnik, Alain Pierre
• Format: Article
• Language: English
• Subjects: Adult; Analysis; Brain research; Care and treatment; Cognition; Cognitive-motor interference; Complications and side effects; Executive function; Exercise Therapy - methods; Gait; Gait disorders; Hospitals; Human health and pathology; Humans; Informed consent; Life Sciences; Magnetic resonance imaging; Motor ability; Multicenter Studies as Topic; Multitask; Protocol; Quality of Life; Randomized Controlled Trials as Topic; Rehabilitation; Risk factors; Stroke; Stroke (Disease); Stroke Rehabilitation - methods; Study Protocol; Treatment Outcome; Walking
• ISSN: 1745-6215; 1745-6215
• DOI: 10.1186/s13063-023-07138-x

Gait disorders and cognitive impairments are prime causes of disability and institutionalization after stroke. We hypothesized that relative to single-task gait rehabilitation (ST GR), cognitive-motor dual-task (DT) GR initiated at the subacute stage would be associated with greater improvements in ST and DT gait, balance, and cognitive performance, personal autonomy, disability, and quality of life in the short, medium and long terms after stroke. This multicenter (n=12), two-arm, parallel-group, randomized (1:1), controlled clinical study is a superiority trial. With p