Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study

The study aims to elucidate the spectrum, magnitude and determining factors of the major opportunistic infections in PLHIV patients currently receiving HAART. A retrospective cross-sectional study was conducted at Tercha Hospital from 744 patient cards. The overall all prevalence of opportunistic in...

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Bibliographic Details
Published in:BMC research notes 2018-08, Vol.11 (1), p.604-604, Article 604
Main Authors: Solomon, Fithamlak Bistegen, Angore, Banchalem Nega, Koyra, Hailu Chare, Tufa, Efrata Girma, Berheto, Tezera Moshago, Admasu, Mahlet
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Adult
AIDS
AIDS-Related Opportunistic Infections - epidemiology
Analysis
Antimicrobial agents
Antiretroviral drugs
Antiretroviral Therapy, Highly Active
Antiviral agents
Associated factors
Candidiasis
CD4 antigen
CD4 Lymphocyte Count
Cross-Sectional Studies
Development and progression
Ethiopia - epidemiology
Female
Health aspects
Hemoglobin
Highly active antiretroviral therapy
HIV
HIV Infections - complications
HIV Infections - drug therapy
HIV patients
Human immunodeficiency virus
Humans
Magnitude
Male
Mortality
Opportunist infection
Opportunistic infections
Patients
PLHIV
Research Note
Retrospective Studies
Spectrum
Tuberculosis
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Summary:The study aims to elucidate the spectrum, magnitude and determining factors of the major opportunistic infections in PLHIV patients currently receiving HAART. A retrospective cross-sectional study was conducted at Tercha Hospital from 744 patient cards. The overall all prevalence of opportunistic infection was 658 (88.4%) developed OIs. Pulmonary tuberculosis, 118 (18%), severe community acquired pneumonia 107 (16.3%) and oral candidiasis 103 (15.6%) were the most common opportunistic infections. Disease stage [AOR = 3.22:95% CI 1.76-5.66], CD4 level [AOR = 2.53:95% CI 1.19-5.37], drug adherence [AOR = 3.02:95% CI 1.57-5.77] and hemoglobin [AOR = 2.49:95% CI 1.34-4.62] showed significant association with OIs. Higher magnitude of opportunistic infection with considerable proportion of AIDS defining illness was detected. So empowerment of skilled man power, health education and provision of antimicrobials is mandatory.
ISSN:1756-0500
1756-0500
DOI:10.1186/s13104-018-3707-9