Polyphenolic profile and biological activity of Chinese hawthorn (Crataegus pinnatifida BUNGE) fruits

Chinese hawthorn (Crataegus pinnatifida Bge.) fruits are rich in polyphenols (e.g., epicatechin, procyanidin B2, procyanidin B5, procyanidin C1, hyperoside, isoquercitrin and chlorogenic acid)--active compounds that exert beneficial effects. This review summarizes all information available on polyph...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2012-12, Vol.17 (12), p.14490-14509
Main Authors: Jurikova, Tunde, Sochor, Jiri, Rop, Otakar, Mlcek, Jiri, Balla, Stefan, Szekeres, Ladislav, Adam, Vojtech, Kizek, Rene
Format: Article
Language:English
Subjects:
Anti-Inflammatory Agents - therapeutic use
antioxidant activity
biological value of fruit
Cardiovascular Diseases - drug therapy
Crataegus pinnatifida
Drugs, Chinese Herbal - chemistry
Drugs, Chinese Herbal - pharmacology
Fruit - chemistry
Humans
Medicine, Traditional
polyphenolic compounds
Polyphenols - chemistry
Polyphenols - isolation & purification
Polyphenols - pharmacology
Review
Rosaceae - chemistry
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Summary:Chinese hawthorn (Crataegus pinnatifida Bge.) fruits are rich in polyphenols (e.g., epicatechin, procyanidin B2, procyanidin B5, procyanidin C1, hyperoside, isoquercitrin and chlorogenic acid)--active compounds that exert beneficial effects. This review summarizes all information available on polyphenolic content and methods for their quantification in Chinese hawthorn berries and the relationships between individual polyphenolic compounds as well. The influence of species or cultivars, the locality of cultivation, the stage of maturity, and extract preparation conditions on the polyphenolic content were discussed as well. Currently, only fruits of C. pinnatifida and C. pinnatifida var. major are included in the Chinese Pharmacopoeia. Recent trials have demonstrated the efficacy of Chinese hawthorn fruit in lowering blood cholesterol and the risk of cardiovascular diseases. The fruit has also demonstrated anti-inflammatory and anti-tumour activities. This review deals mainly with the biological activity of the fruit related to its antioxidant properties.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules171214490