Corpus Callosum Abnormalities at Term-Equivalent Age Are Associated with Language Development at 2 Years' Corrected Age in Infants Born Very Preterm

We studied the effect of microstructural abnormalities in the corpus callosum on language development in 348 infants born very prematurely. We discovered that the fractional anisotropy of the corpus callosum anterior midbody was a significant predictor of standardized language scores at 2 years, ind...

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Bibliographic Details
Published in:Journal of pediatrics. Clinical practice 2024-03, Vol.11, p.200101-200101, Article 200101
Main Authors: Kojima, Katsuaki, Kline, Julia E, Altaye, Mekibib, Kline-Fath, Beth M, Parikh, Nehal A
Format: Article
Language:English
Subjects:
Bayley-III
diffusion tensor imaging
infant
neurodevelopmental outcome
newborn
preterm
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Summary:We studied the effect of microstructural abnormalities in the corpus callosum on language development in 348 infants born very prematurely. We discovered that the fractional anisotropy of the corpus callosum anterior midbody was a significant predictor of standardized language scores at 2 years, independent of clinical and social risk factors.
ISSN:2950-5410
2950-5410
DOI:10.1016/j.jpedcp.2024.200101