Haplotype Diversity of Mitochondrial DNA in the Jat Population of Haryana

The genetic representation of various population groups has been successfully attempted by studying hypervariable regions of human mitochondrial DNA (mtDNA) for forensic purposes. In this view of the fact, there are very few studies in the northern region of India focusing on mtDNA variations. The u...

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Bibliographic Details
Published in:Journal of forensic science and medicine 2023-10, Vol.9 (4), p.320-330
Main Authors: Sharma, Sapna, Verma, Kapil
Format: Article
Language:English
Subjects:
Analysis
Ethylenediaminetetraacetic acid
forensic
Genetic aspects
hvi
hvii
hviii
hypervariable regions
Mitochondrial DNA
Phylogeny
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Summary:The genetic representation of various population groups has been successfully attempted by studying hypervariable regions of human mitochondrial DNA (mtDNA) for forensic purposes. In this view of the fact, there are very few studies in the northern region of India focusing on mtDNA variations. The usage of mtDNA typing for forensic purposes has however been delayed in most states, especially Haryana, due to lack of mtDNA pool database for Haryana populations. Since, there has been no elaborated mtDNA study on Jat population of Haryana, thus, the genetic variability of Jat population of Haryana was estimated by examining the hypervariable regions (HVI, HVII, and HVIII) of mtDNA. Blood samples of maternally unrelated individuals have been collected. The polymorphism has been observed with their corresponding haplogroups. The phylogenetic relationship was inferred between different haplogroups. A high level of variation and a low random match probability was observed in all the three hypervariable regions of mtDNA, indicating its utility for forensic purposes.
ISSN:2349-5014
2455-0094
DOI:10.4103/jfsm.jfsm_4_22