Discovery of Novel Alphacoronaviruses in European Rodents and Shrews

Eight hundred and thirteen European rodents and shrews encompassing seven different species were screened for alphacoronaviruses using PCR detection. Novel alphacoronaviruses were detected in the species Rattus norvegicus, Microtus agrestis, Sorex araneus and Myodes glareolus. These, together with t...

Full description

Saved in:
Bibliographic Details
Published in:Viruses 2016-03, Vol.8 (3), p.84-84
Main Authors: Tsoleridis, Theocharis, Onianwa, Okechukwu, Horncastle, Emma, Dayman, Emma, Zhu, Miaoran, Danjittrong, Taechasit, Wachtl, Marta, Behnke, Jerzy M, Chapman, Sarah, Strong, Victoria, Dobbs, Phillipa, Ball, Jonathan K, Tarlinton, Rachael E, McClure, C Patrick
Format: Article
Language:English
Subjects:
alphacoronavirus
Animals
Communication
Coronavirus - classification
Coronavirus - isolation & purification
Coronavirus Infections - veterinary
Coronavirus Infections - virology
coronaviruses
Europe
Genotype
Mass Screening
Phylogeny
Polymerase Chain Reaction
Rodentia - virology
rodents
Sequence Analysis, DNA
shrews
Shrews - virology
Viral Proteins - genetics
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Eight hundred and thirteen European rodents and shrews encompassing seven different species were screened for alphacoronaviruses using PCR detection. Novel alphacoronaviruses were detected in the species Rattus norvegicus, Microtus agrestis, Sorex araneus and Myodes glareolus. These, together with the recently described Lucheng virus found in China, form a distinct rodent/shrew-specific clade within the coronavirus phylogeny. Across a highly conserved region of the viral polymerase gene, the new members of this clade were up to 22% dissimilar at the nucleotide level to the previously described Lucheng virus. As such they might represent distinct species of alphacoronaviruses. These data greatly extend our knowledge of wildlife reservoirs of alphacoronaviruses.
ISSN:1999-4915
1999-4915
DOI:10.3390/v8030084