Applications and challenges of low temperature plasma in pharmaceutical field

Low temperature plasma (LTP) technology has shown an outstanding application value in the pharmaceutical filed in recent ten years. This paper reviews the research advances in LTP, including its effects on enhancing or inhibiting drug activity, its combined use with drugs to treat cancers, its effec...

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Bibliographic Details
Published in:Journal of pharmaceutical analysis 2021-02, Vol.11 (1), p.28-36
Main Authors: Gao, Lingge, Shi, Xingmin, Wu, Xili
Format: Article
Language:English
Subjects:
Drug delivery system
Low temperature plasma
Nanodrug
Pharmacy
Plasma-activated liquids
Review Paper
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Summary:Low temperature plasma (LTP) technology has shown an outstanding application value in the pharmaceutical filed in recent ten years. This paper reviews the research advances in LTP, including its effects on enhancing or inhibiting drug activity, its combined use with drugs to treat cancers, its effects on the improvement of drug delivery system, its use in preparation of new inactivated virus vaccines, its use with mass spectrometry for rapid detection of drug quality, and the anti-tumor and sterilization effects of plasma-activated liquids. The paper also analyzes the challenges of LTP in the pharmaceutical filed, hoping to promote related research. [Display omitted] •Low temperature plasma is a young subject. It shows infinite possibilities in many fields.•Paper introduces the research advances on low temperature plasma in pharmaceutical field for the first time.•Paper summarizes the difficulties in the application of low temperature plasma in pharmacy.
ISSN:2095-1779
2214-0883
DOI:10.1016/j.jpha.2020.05.001