The Epidemiology and Outcome of Biliary Atresia: Saudi Arabian National Study (2000–2018)

BackgroundThe epidemiology and outcomes of biliary atresia (BA) have been well-documented in national cohorts from two main ethnicities, namely, the Asian Orientals and Caucasians, with incidence ranging from 1 in 5,000 to 1 in 9,000 live births in East Asia and 1 in 15,000 to 19,000 live births in...

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Published in:Frontiers in pediatrics 2022-07, Vol.10, p.921948-921948
Main Authors: Al-Hussaini, Abdulrahman, Abanemai, Mohammed, Alhebbi, Homoud, Saadah, Omar, Bader, Razan, Al Sarkhy, Ahmed, Alhatlani, Maher, Halabi, Hana, Aladsani, Ahmed, AlEdreesi, Mohammed, Wali, Sami, Alguofi, Talal, Al-drees, Khalid, Arain, Zahid, Al Saleem, Badr, Asery, Ali, Holdar, Sinan, Alrashidi, Sami, Alsayed, Fahad, Aldhalan, Sulaiman, NasserAllah, Amira, Alghamdi, Rawabi, Alhaffaf, Faisal, AlAwfi, Ahmed, AlSweed, Abdulrahman, Alshamrani, Ali, AlShaikh, Manal, Saeed, Anjum, Assiri, Heba, Bashir, Muhammed Salman
Format: Article
Language:English
Subjects:
Arabs
biliary atresia
Kasai portoenterostomy
liver transplantation
neonatal cholestasis
Pediatrics
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Summary:BackgroundThe epidemiology and outcomes of biliary atresia (BA) have been well-documented in national cohorts from two main ethnicities, namely, the Asian Orientals and Caucasians, with incidence ranging from 1 in 5,000 to 1 in 9,000 live births in East Asia and 1 in 15,000 to 19,000 live births in Europe and North America. ObjectiveWe report the first nationwide BA study outside North America, Europe, and East Asia to describe the epidemiology and outcomes of BA in Saudi Arabia. MethodsA national database of BA cases diagnosed between 2000 and 2018 was analyzed. We assessed clearance of jaundice (bilirubin
ISSN:2296-2360
2296-2360
DOI:10.3389/fped.2022.921948