A Guide to a Pharmacist-Led Pharmacogenetic Testing and Counselling Service in an Interprofessional Healthcare Setting

Genetic predisposition is one factor influencing interindividual drug response. Pharmacogenetic information can be used to guide the selection and dosing of certain drugs. However, the implementation of pharmacogenetics (PGx) in clinical practice remains challenging. Defining a formal structure, as...

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Bibliographic Details
Published in:Pharmacy 2022-07, Vol.10 (4), p.86
Main Authors: Stäuble, Céline K, Jeiziner, Chiara, Bollinger, Anna, Wiss, Florine M, Hatzinger, Martin, Hersberger, Kurt E, Ihde, Thomas, Lampert, Markus L, Mikoteit, Thorsten, Meyer Zu Schwabedissen, Henriette E, Allemann, Samuel S
Format: Article
Language:English
Subjects:
Analysis
Clinical medicine
clinical pharmacy
Counseling
Drug dosages
Drug interactions
Drug stores
Drug therapy
Enzymes
Family physicians
Influence
Interpersonal relations
Intervention
Medical referrals
medication review
Metabolism
Methods
Patient compliance
personalized medicine
pharmaceutical care
Pharmacists
Pharmacodynamics
Pharmacogenetics
pharmacogenomics
Pharmacokinetics
pharmacy service
Physicians
Practice
Prescription drugs
Professionals
Psychiatric services
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Summary:Genetic predisposition is one factor influencing interindividual drug response. Pharmacogenetic information can be used to guide the selection and dosing of certain drugs. However, the implementation of pharmacogenetics (PGx) in clinical practice remains challenging. Defining a formal structure, as well as concrete procedures and clearly defined responsibilities, may facilitate and increase the use of PGx in clinical practice. Over 140 patient cases from an observational study in Switzerland formed the basis for the design and refinement of a pharmacist-led pharmacogenetics testing and counselling service (PGx service) in an interprofessional setting. Herein, we defined a six-step approach, including: (1) patient referral; (2) pre-test-counselling; (3) PGx testing; (4) medication review; (5) counselling; (6) follow-up. The six-step approach supports the importance of an interprofessional collaboration and the role of pharmacists in PGx testing and counselling across healthcare settings.
ISSN:2226-4787
2226-4787
DOI:10.3390/pharmacy10040086