Tunable, Low–Cost, Multi–Channel, Broadband Liquid Crystal Shutter for Fluorescence Imaging in Widefield Microscopy

Bistable liquid crystal (LC) shutters have attracted much interest due to their low energy consumption and fast response time. In this paper, we demonstrate an electrically tunable/switchable biostable LC light shutter in biological optics through a three–step easy–assembly, inexpensive, multi–chann...

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Bibliographic Details
Published in:Micromachines (Basel) 2022-08, Vol.13 (8), p.1310
Main Authors: Gong, Yan, Li, Bo, Yao, Cheng-You, Yang, Weiyang, Fan, Qi Hua, Qiu, Zhen, Li, Wen
Format: Article
Language:English
Subjects:
Broadband
Cameras
Chemical vapor deposition
Comparative analysis
Electrodes
Energy consumption
Fluorescence
fluorescence imaging
Fluorescence microscopy
Indium tin oxides
Infrared imagery
Light
liquid crystal shutter
Liquid crystals
Luminous intensity
Medical imaging
Microscopy
nematic liquid crystal
Polyethylene terephthalate
Response time
Shutters
tumor imaging
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Description
Summary:Bistable liquid crystal (LC) shutters have attracted much interest due to their low energy consumption and fast response time. In this paper, we demonstrate an electrically tunable/switchable biostable LC light shutter in biological optics through a three–step easy–assembly, inexpensive, multi–channel shutter. The liquid crystal exhibits tunable transparency (100% to 10% compared to the initial light intensity) under different voltages (0 V to 90 V), indicating its tunable potential. By using biomedical images, the response time, resolution, and light intensity changes of the LC under different voltages in three common fluorescence wavelengths are displayed intuitively. Particularly, the shutter’s performance in tumor images under the near–infrared band shows its application potential in biomedical imaging fields.
ISSN:2072-666X
2072-666X
DOI:10.3390/mi13081310