Association of Body Mass Index with Outcomes in Patients with Atrial Fibrillation: Analysis from the (JoFib) Registry

• Published in: Vascular health and risk management 2024-01, Vol.20, p.89-96
• Main Authors: Ibdah, Rashid, Alghzawi, Ahmad Abdalmajeed, Atoum, Amer K, Alenazi, Lina Ib, Al Omary, Anwar Y, Hammoudeh, Ayman, Laswi, Bushra, Rawashdeh, Sukaina
• Format: Article
• Language: English
• Subjects: Adult; Analysis; Anticoagulants (Medicine); Anticoagulants - adverse effects; Atrial fibrillation; Atrial Fibrillation - epidemiology; Body Mass Index; Care and treatment; clinical outcome; Comorbidity; complications; Humans; Hypertension; Male; Middle East; Mortality; Obesity; Obesity - epidemiology; Original Research; paradox; Patient outcomes; Prognosis; Registries; Risk Factors; Type 2 diabetes
• ISSN: 1178-2048; 1176-6344; 1178-2048
• DOI: 10.2147/VHRM.S444894

Atrial fibrillation (AF) accounts for the majority of arrhythmias affecting adults. It is associated with an increased mortality and various complications. Obesity being a major risk factor of cardiovascular and metabolic diseases including AF has always been connected to the overall burden of AF, but its role in the development of AF complications remains unclear. Our study aims to evaluate the impact of obesity on the complications of AF in Jordanian patients to establish a proper prognosis since studies regarding this topic in the Middle East are scant. This study analyzed data from the Jordanian AF study (JoFib), which enrolled Jordanians with AF. Clinical characteristics were compared among patients who developed complications and those who did not. A binary logistic regression analysis was conducted to identify factors associated with AF complications development. 1857 patients were enrolled. There was no significant difference in BMI value between patients who developed complications and those who did not. Male sex, old age, hypertension, diabetes mellitus, and higher risk scores were associated with increased odds of developing complications. The oral anticoagulant use was found to be protective. Smoking had no significant effect on odds of complications. The study concludes that increased BMI is not significantly associated with a reduced risk of developing AF complications. Further research with longer follow-up and larger sample sizes is needed to confirm these results.