The Modifiable Risk Factors of Uncontrolled Hypertension in Stroke: A Systematic Review and Meta-Analysis

Objective. This review aimed at figuring out the risk factors of uncontrolled hypertension in stroke. Method. This study systematically analyzed the hypertension risk factors available in the ProQuest, EBSCO, and PubMed databases published between 2010 and December 2019. The risk factors’ pooled odd...

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Bibliographic Details
Published in:Stroke research and treatment 2021, Vol.2021, p.6683256-11
Main Authors: Upoyo, Arif Setyo, Setyopranoto, Ismail, Pangastuti, Heny Suseani
Format: Article
Language:English
Subjects:
Age
Alcohol
Antihypertensives
Atrial fibrillation
Bias
Blood pressure
Cardiac arrhythmia
Database industry
Diabetes
Drugs
Hypertension
Information management
Medical research
Medicine, Experimental
Meta-analysis
Metabolic syndrome
Obesity
Patient compliance
Review
Risk factors
Smoking
Stroke
Systematic review
Triglycerides
Variables
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Summary:Objective. This review aimed at figuring out the risk factors of uncontrolled hypertension in stroke. Method. This study systematically analyzed the hypertension risk factors available in the ProQuest, EBSCO, and PubMed databases published between 2010 and December 2019. The risk factors’ pooled odds ratio (POR) included in this research was calculated using both fixed and random-effect models. The meta-data analysis was processed using the Review Manager 5.3 (Rev Man 5.3). Result. Of 1868 articles, seven studies were included in this review searched using specific keywords. Based on the analysis results, there were 7 risk factors of uncontrolled hypertension in stroke: medication nonadherence (POR=2.23 [95% CI 1.71-2.89], p=0.342; I2=6.7%), use of antihypertensive drugs (POR=1.13 [95% CI 1.19-1.59, p=0.001; I2=90.9%), stage of hypertension (POR=1.14 [95% CI 1.02-1.27], p=
ISSN:2090-8105
2042-0056
2042-0056
DOI:10.1155/2021/6683256