Exploring the Role of Poly (N-vinyl pyrrolidone) in Drug Delivery

Polyvinylpyrrolidone (PVP) is widely recognized for its hydrophilic properties, making it essential in pharmaceutical and biomedical industries as a carrier material. This review examines PVP-enriched delivery systems, emphasizing their capacity to integrate diverse active agents from both organic a...

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Bibliographic Details
Published in:Chemical and biochemical engineering quarterly 2024-07, Vol.38 (3), p.185-196
Main Authors: Mikayilov, E, Tagiyev, D, Zeynalov, N, Tagiyev, Sh
Format: Article
Language:English
Subjects:
Chemical research
computational modeling
drug delivery
Drug delivery systems
Drugs
hydrogels
nanoparticles
polyvinylpyrrolidone (PVP)
Povidone
Vehicles
Online Access:Get full text
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Summary:Polyvinylpyrrolidone (PVP) is widely recognized for its hydrophilic properties, making it essential in pharmaceutical and biomedical industries as a carrier material. This review examines PVP-enriched delivery systems, emphasizing their capacity to integrate diverse active agents from both organic and synthetic sources. The versatility of PVP is showcased through its use in different formulations, such as microparticles, nanoparticles, fibrous structures, hydrogels, and tablets, which emphasize its potential in innovative drug delivery mechanisms. The review thoroughly examines the customized morphologies for specific PVP-drug combinations, detailing the active agents, methodologies, and processing parameters used. It discusses the advantages and challenges of these systems, underscoring the polymer's significant role in novel pharmaceutical product development. Overall, this detailed analysis confirms PVP's critical position in advancing drug delivery technologies, showcasing its multifaceted applications and potential for pioneering new treatments. Keywords nanoparticles, hydrogels, computational modeling, polyvinylpyrrolidone (PVP), drug delivery
ISSN:0352-9568
0352-9568
1846-5153
DOI:10.15255/CABEQ.2024.2331