Predictive role of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios for diagnosis of acute appendicitis during pregnancy

Abstract Acute appendicitis (AA) is not uncommon during pregnancy but can be difficult to diagnose. This study evaluated the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in addition to conventional diagnostic indicators of the disease to diagnose AA during pregnancy. A...

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Published in:The Kaohsiung journal of medical sciences 2015-11, Vol.31 (11), p.591-596
Main Authors: Yazar, Fatih Mehmet, Bakacak, Murat, Emre, Arif, Urfalıoglu, Aykut, Serin, Salih, Cengiz, Emrah, Bülbüloglu, Ertan
Format: Article
Language:English
Subjects:
Acute appendicitis
Acute Disease
Adult
Alvarado scores
Appendicitis - blood
Appendicitis - diagnosis
C-Reactive Protein - metabolism
Female
Humans
Internal Medicine
Leukocyte Count
Logistic Models
Lymphocytes - pathology
Neutrophil-to-lymphocyte ratio
Neutrophils - pathology
Platelet-to-lymphocyte ratio
Pregnancy
ROC Curve
Sensitivity and Specificity
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Summary:Abstract Acute appendicitis (AA) is not uncommon during pregnancy but can be difficult to diagnose. This study evaluated the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in addition to conventional diagnostic indicators of the disease to diagnose AA during pregnancy. Age, gestational age, white blood cell (WBC) count, Alvarado scores, C-reactive protein (CRP), lymphocyte count, NLR and PLR were compared among 28 pregnant women who underwent surgery for AA, 35 pregnant women wrongly suspected as having AA, 29 healthy pregnant women, and 30 nonpregnant healthy women. Mean WBC counts and CRP levels were higher in women with proven AA than in those of control groups (all p  
ISSN:1607-551X
2410-8650
DOI:10.1016/j.kjms.2015.10.005