Revolutionizing Precision Medicine: Exploring Wearable Sensors for Therapeutic Drug Monitoring and Personalized Therapy

Precision medicine, particularly therapeutic drug monitoring (TDM), is essential for optimizing drug dosage and minimizing toxicity. However, current TDM methods have limitations, including the need for skilled operators, patient discomfort, and the inability to monitor dynamic drug level changes. I...

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Bibliographic Details
Published in:Biosensors (Basel) 2023-07, Vol.13 (7), p.726
Main Authors: Liu, Yuqiao, Li, Junmin, Xiao, Shenghao, Liu, Yanhui, Bai, Mingxia, Gong, Lixiu, Zhao, Jiaqian, Chen, Dajing
Format: Article
Language:English
Subjects:
Accuracy
Alzheimer's disease
Antibiotics
Biosensors
Catalysis
Chromatography
Comparative analysis
Customization
Dopamine
drug analysis
Drug dosages
Drug utilization
Electrodes
Enzymes
Evaluation
Health care
Medicine
Metabolism
Metabolites
Monitoring
Optimization
Parkinson's disease
personalized medicine
Pharmacokinetics
Precision medicine
Real time
Review
Risk reduction
Sensors
Technology application
Telemedicine
Therapeutic drug monitoring
Time measurement
Toxicity
Voltammetry
wearable sensors
Wearable technology
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Summary:Precision medicine, particularly therapeutic drug monitoring (TDM), is essential for optimizing drug dosage and minimizing toxicity. However, current TDM methods have limitations, including the need for skilled operators, patient discomfort, and the inability to monitor dynamic drug level changes. In recent years, wearable sensors have emerged as a promising solution for drug monitoring. These sensors offer real-time and continuous measurement of drug concentrations in biofluids, enabling personalized medicine and reducing the risk of toxicity. This review provides an overview of drugs detectable by wearable sensors and explores biosensing technologies that can enable drug monitoring in the future. It presents a comparative analysis of multiple biosensing technologies and evaluates their strengths and limitations for integration into wearable detection systems. The promising capabilities of wearable sensors for real-time and continuous drug monitoring offer revolutionary advancements in diagnostic tools, supporting personalized medicine and optimal therapeutic effects. Wearable sensors are poised to become essential components of healthcare systems, catering to the diverse needs of patients and reducing healthcare costs.
ISSN:2079-6374
2079-6374
DOI:10.3390/bios13070726