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Health Benefits of Nut Consumption in Middle-Aged and Elderly Population
Aging is considered the major risk factor for most chronic disorders. Oxidative stress and chronic inflammation are two major contributors for cellular senescence, downregulation of stress response pathways with a decrease of protective cellular activity and accumulation of cellular damage, leading...
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Published in: | Antioxidants 2019-08, Vol.8 (8), p.302 |
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description | Aging is considered the major risk factor for most chronic disorders. Oxidative stress and chronic inflammation are two major contributors for cellular senescence, downregulation of stress response pathways with a decrease of protective cellular activity and accumulation of cellular damage, leading in time to age-related diseases. This review investigated the most recent clinical trials and cohort studies published in the last ten years, which presented the influence of tree nut and peanut antioxidant diets in preventing or delaying age-related diseases in middle-aged and elderly subjects (≥55 years old). Tree nut and peanut ingestion has the possibility to influence blood lipid count, biochemical and anthropometric parameters, endothelial function and inflammatory biomarkers, thereby positively affecting cardiometabolic morbidity and mortality, cancers, and cognitive disorders, mainly through the nuts' healthy lipid profile and antioxidant and anti-inflammatory mechanisms of actions. Clinical evidence and scientific findings demonstrate the importance of diets characterized by a high intake of nuts and emphasize their potential in preventing age-related diseases, validating the addition of tree nuts and peanuts in the diet of older adults. Therefore, increased consumption of bioactive antioxidant compounds from nuts clearly impacts many risk factors related to aging and can extend health span and lifespan. |
doi_str_mv | 10.3390/antiox8080302 |
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Oxidative stress and chronic inflammation are two major contributors for cellular senescence, downregulation of stress response pathways with a decrease of protective cellular activity and accumulation of cellular damage, leading in time to age-related diseases. This review investigated the most recent clinical trials and cohort studies published in the last ten years, which presented the influence of tree nut and peanut antioxidant diets in preventing or delaying age-related diseases in middle-aged and elderly subjects (≥55 years old). Tree nut and peanut ingestion has the possibility to influence blood lipid count, biochemical and anthropometric parameters, endothelial function and inflammatory biomarkers, thereby positively affecting cardiometabolic morbidity and mortality, cancers, and cognitive disorders, mainly through the nuts' healthy lipid profile and antioxidant and anti-inflammatory mechanisms of actions. Clinical evidence and scientific findings demonstrate the importance of diets characterized by a high intake of nuts and emphasize their potential in preventing age-related diseases, validating the addition of tree nuts and peanuts in the diet of older adults. Therefore, increased consumption of bioactive antioxidant compounds from nuts clearly impacts many risk factors related to aging and can extend health span and lifespan.</description><identifier>ISSN: 2076-3921</identifier><identifier>EISSN: 2076-3921</identifier><identifier>DOI: 10.3390/antiox8080302</identifier><identifier>PMID: 31409026</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>age-related diseases ; Aging ; Antioxidants ; biomarkers ; blood lipids ; Cardiovascular disease ; cell senescence ; Cellular stress response ; Cholesterol ; Clinical trials ; Cognitive ability ; cognitive disorders ; cohort studies ; Diabetes ; Diet ; elderly ; Geriatrics ; Heart ; Inflammation ; ingestion ; Life span ; lipid composition ; longevity ; Meta-analysis ; Middle age ; middle-aged population ; Morbidity ; Mortality ; neoplasms ; nut-enriched Mediterranean diet ; Nuts ; Older people ; Oxidative stress ; Peanuts ; Phytochemicals ; Population ; Review ; Risk factors ; Senescence ; stress response ; Stroke ; tree nuts ; Womens health</subject><ispartof>Antioxidants, 2019-08, Vol.8 (8), p.302</ispartof><rights>2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). 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Oxidative stress and chronic inflammation are two major contributors for cellular senescence, downregulation of stress response pathways with a decrease of protective cellular activity and accumulation of cellular damage, leading in time to age-related diseases. This review investigated the most recent clinical trials and cohort studies published in the last ten years, which presented the influence of tree nut and peanut antioxidant diets in preventing or delaying age-related diseases in middle-aged and elderly subjects (≥55 years old). Tree nut and peanut ingestion has the possibility to influence blood lipid count, biochemical and anthropometric parameters, endothelial function and inflammatory biomarkers, thereby positively affecting cardiometabolic morbidity and mortality, cancers, and cognitive disorders, mainly through the nuts' healthy lipid profile and antioxidant and anti-inflammatory mechanisms of actions. Clinical evidence and scientific findings demonstrate the importance of diets characterized by a high intake of nuts and emphasize their potential in preventing age-related diseases, validating the addition of tree nuts and peanuts in the diet of older adults. Therefore, increased consumption of bioactive antioxidant compounds from nuts clearly impacts many risk factors related to aging and can extend health span and lifespan.</description><subject>age-related diseases</subject><subject>Aging</subject><subject>Antioxidants</subject><subject>biomarkers</subject><subject>blood lipids</subject><subject>Cardiovascular disease</subject><subject>cell senescence</subject><subject>Cellular stress response</subject><subject>Cholesterol</subject><subject>Clinical trials</subject><subject>Cognitive ability</subject><subject>cognitive disorders</subject><subject>cohort studies</subject><subject>Diabetes</subject><subject>Diet</subject><subject>elderly</subject><subject>Geriatrics</subject><subject>Heart</subject><subject>Inflammation</subject><subject>ingestion</subject><subject>Life span</subject><subject>lipid composition</subject><subject>longevity</subject><subject>Meta-analysis</subject><subject>Middle age</subject><subject>middle-aged population</subject><subject>Morbidity</subject><subject>Mortality</subject><subject>neoplasms</subject><subject>nut-enriched Mediterranean diet</subject><subject>Nuts</subject><subject>Older people</subject><subject>Oxidative stress</subject><subject>Peanuts</subject><subject>Phytochemicals</subject><subject>Population</subject><subject>Review</subject><subject>Risk factors</subject><subject>Senescence</subject><subject>stress response</subject><subject>Stroke</subject><subject>tree nuts</subject><subject>Womens health</subject><issn>2076-3921</issn><issn>2076-3921</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqFkkFv1DAQRiMEolXpkSuKxIVLytiTOPEFqawKW6kFDnC2JvFkm5XXXuykov-ebLdU3V7wxZb99PSN9WXZWwFniBo-kh-H8KeBBhDki-xYQq0K1FK8fHI-yk5TWsO8tMAG9OvsCEUJGqQ6zpZLJjfe5J_Zcz-MKQ99_m0a80XwadpsZ73PB59fD9Y6Ls5XbHPyNr9wlqO7y3-E7eRoR73JXvXkEp8-7CfZry8XPxfL4ur718vF-VXRVaIcC9WVLbFuKxISSqwqTaj7nhg7xcoitpJZVb2srZWI1jZMbLluxC5vJ_Eku9x7baC12cZhQ_HOBBrM_UWIK0NxHDrHBhpNSltqoW5KtroFlAJZQUkWW1XPrk9713ZqN2w79mMkdyA9fPHDjVmFW6NqoUWFs-DDgyCG3xOn0WyG1LFz5DlMycgSoJpzN_X_UVmjhEbADn3_DF2HKfr5V42syllWV6BnqthTXQwpRe4fcwswu3aYg3bM_Lunwz7S_7qAfwG5UrUx</recordid><startdate>20190812</startdate><enddate>20190812</enddate><creator>Rusu, Marius Emil</creator><creator>Mocan, Andrei</creator><creator>Ferreira, Isabel C F R</creator><creator>Popa, Daniela-Saveta</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QR</scope><scope>7T5</scope><scope>7TO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M7P</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>7S9</scope><scope>L.6</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0001-5848-8457</orcidid><orcidid>https://orcid.org/0000-0003-4910-4882</orcidid><orcidid>https://orcid.org/0000-0002-0880-9889</orcidid></search><sort><creationdate>20190812</creationdate><title>Health Benefits of Nut Consumption in Middle-Aged and Elderly Population</title><author>Rusu, Marius Emil ; 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subjects | age-related diseases Aging Antioxidants biomarkers blood lipids Cardiovascular disease cell senescence Cellular stress response Cholesterol Clinical trials Cognitive ability cognitive disorders cohort studies Diabetes Diet elderly Geriatrics Heart Inflammation ingestion Life span lipid composition longevity Meta-analysis Middle age middle-aged population Morbidity Mortality neoplasms nut-enriched Mediterranean diet Nuts Older people Oxidative stress Peanuts Phytochemicals Population Review Risk factors Senescence stress response Stroke tree nuts Womens health |
title | Health Benefits of Nut Consumption in Middle-Aged and Elderly Population |
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