Editorial: Oscillotherapeutics - toward real-time control of pathological oscillations in the brain

• Published in: Frontiers in behavioral neuroscience 2022-09, Vol.16, p.1021616-1021616
• Main Authors: Takeuchi, Yuichi, Li, Qun, Kawano, Takeshi, Nagai, Jun, Mima, Tatsuya
• Format: Article
• Language: English
• Subjects: Addictions; Alzheimer's disease; Autism; Behavioral Neuroscience; Biomarkers; Brain research; brain stimulation; c-Fos protein; closed-loop control; Conflicts of interest; Cortex (parietal); Editorials; Epilepsy; Mental disorders; Movement disorders; Neural networks; Neurodegenerative diseases; Neurological diseases; neurological disorders; Neuronal-glial interactions; oscillation; Oscillations; oscillopathy; Parkinson's disease; Pharmaceuticals; Phenotypes; Physiology; psychiatric disorders; Schizophrenia; Transgenic mice; Trauma
• ISSN: 1662-5153; 1662-5153
• DOI: 10.3389/fnbeh.2022.1021616

Abnormal oscillatory brain activities are commonly observed in neurological and psychiatric disorders including epilepsy, Parkinson's disease, Alzheimer's disease, schizophrenia, anxiety/trauma-related disorders, major depressive disorders, and addiction (Leuchter et al., 2015; Takeuchi et al., 2021b). [...]these disorders can be considered as common oscillation defects “oscillopathies,” despite having distinct behavioral manifestations (Takeuchi and Berényi, 2020; Földi et al., 2021). Wada et al. reported diminished “rubber tail task”-related expression of the immediate early gene (c-Fos) in the posterior parietal cortex of a transgenic mouse line that exhibits autistic-like phenotypes. Commun. 9, 483. doi: 10.1038/s41467-018-02928-3 Yuichi Takeuchi1,2*, Qun Li2, Takeshi Kawano3, Jun Nagai4 and Tatsuya Mima5 * 1Department of Biopharmaceutical Sciences and Pharmacy, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan * 2MTA-SZTE “Momentum” Oscillatory Neuronal Networks Research Group, Department of Physiology, University of Szeged, Szeged, Hungary * 3Department of Electrical and Electronic Information Engineering, Toyohashi University of Technology, Aichi, Japan * 4Laboratory for Glia-Neuron Circuit Dynamics, RIKEN Center for Brain Science, Saitama, Japan * 5The Graduate School of Core Ethics and Frontier Sciences, Ritsumeikan University, Kyoto, Japan