Efficacy and safety of small-incision corneal intrastromal lenticule implantation for hyperopia correction: a systematic review and meta-analysis

• Published in: Frontiers in medicine 2024, Vol.11, p.1320235-1320235
• Main Authors: Wang, Yue, Zheng, Jingjing, Guo, Zuofeng, Fang, Xuejun
• Format: Article
• Language: English
• Subjects: hyperopia; lenticule implantation; meta-analysis; refractive; small incision lenticule extraction
• ISSN: 2296-858X; 2296-858X
• DOI: 10.3389/fmed.2024.1320235

To assess the efficacy and safety of intrastromal lenticule implantation for the treatment of hyperopia. A systematic search of PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Internet, and Wan Fang Database identified studies on small-incision intrastromal lenticule implantation for hyperopia correction until January 2023. The Joanna Briggs Institute (JBI) critical appraisal tool was used to assess the quality of the retrospective research, and the Methodological Index for Non-randomized Studies (MINORS) was used to assess the quality of the prospective research. This study included postoperative visual outcomes, corneal morphology, and biomechanical outcomes. A total of 456 articles were identified, of which 10 were included in the meta-analysis. Ten single-arm studies involving 190 eyes were included. A meta-analysis demonstrated that corneal intrastromal lenticule implantation treatment significantly improved hyperopia. Uncorrected distance visual acuity (UDVA) significantly improved compared to the preoperative value (  = 0.027), corrected distance visual acuity showed no difference compared to the preoperative value (  = 0.27), and 87% eyes have no loss of one or more lines in the Snellen lines of CDVA (