Histopathological Changes in the Myocardium Caused by Energy Drinks and Alcohol in the Mid-term and Their Effects on Skeletal Muscle Following Ischemia-reperfusion in a Rat Model

Although energy drinks have been consumed for many years, their effects on the cardiovascular system continue to be investigated. Today, the most frequently used area of energy drinks is the entertainment sector, and this study investigates the effects of energy drinks and alcohol consumption on rat...

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Bibliographic Details
Published in:Anatolian journal of cardiology 2023-01, Vol.27 (1), p.12-18
Main Authors: Demirel, Aylin, Başgöze, Serdar, Çakıllı, Kübra, Aydın, Ünal, Erkanlı Şentürk, Gözde, Örnek Diker, Vesile, Ertürk, Mehmet
Format: Article
Language:English
Subjects:
alcohol
Animals
energy drinks
Energy Drinks - adverse effects
Ethanol
Ischemia
ischemia–reperfusion
Muscle, Skeletal
Myocardium
Original Investigation
rat
Rats
Rats, Wistar
Reperfusion
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Summary:Although energy drinks have been consumed for many years, their effects on the cardiovascular system continue to be investigated. Today, the most frequently used area of energy drinks is the entertainment sector, and this study investigates the effects of energy drinks and alcohol consumption on rats' limb and myocardium tissue. Forty Wistar Albino rats were used and divided into 4 groups. Energy drinks were given to the first group (the energy drink group), alcohol was given to the second group, and energy drinks and alcohol were given to the third group Redbull-Alcohol (RA). Blood samples, leg muscles, and heart tissues were studied after the ischemia-reperfusion model was created at the infrarenal level. In the histopathological examination of heart muscles, the damage was significantly more severe in the RA group than in the control group (P
ISSN:2149-2263
2149-2271
DOI:10.14744/AnatolJCardiol.2022.2003