Management of Thyroid Peroxidase Antibody Euthyroid Women in Pregnancy: Comparison of the American Thyroid Association and the Endocrine Society Guidelines

The presence of thyroid autoantibodies is relatively high in women of childbearing age. There is evidence that positive thyroperoxidase antibody even in euthyroid women may increase the risk of spontaneous and recurrent pregnancy loss and preterm delivery. However, the evidence is not enough to just...

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Bibliographic Details
Published in:Journal of Thyroid Research 2013-01, Vol.2013 (2013), p.106-111
Main Authors: Mehran, Ladan, Tohidi, M., Sarvghadi, Farzaneh, Delshad, Hossein, Amouzegar, Atieh, Soldin, Offie P., Azizi, Fereidoun
Format: Article
Language:English
Subjects:
Age
Antibodies
Autoantibodies
Care and treatment
Clinical medicine
Health aspects
Hypothyroidism
In vitro fertilization
Iodine
Miscarriage
Pregnancy complications
Pregnant women
Review
Risk factors
Society
Thyroid diseases
Womens health
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Summary:The presence of thyroid autoantibodies is relatively high in women of childbearing age. There is evidence that positive thyroperoxidase antibody even in euthyroid women may increase the risk of spontaneous and recurrent pregnancy loss and preterm delivery. However, the evidence is not enough to justify recommendation on the screening of pregnant women for thyroid autoantibodies or LT4 supplementation for reducing maternal or fetal complications. In this paper we reviewed the related evidence and compared the new guidelines of the American Thyroid Association and Endocrine Society with respect to the screening and management of positive thyroperoxidase antibody in euthyroid pregnant women. As there was no major contradiction or disagreement between the two guidelines, either one of two guidelines may be used by clinicians for the appropriate management of thyroid autoimmunity during pregnancy.
ISSN:2042-0072
2090-8067
2042-0072
DOI:10.1155/2013/542692