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Management of Thyroid Peroxidase Antibody Euthyroid Women in Pregnancy: Comparison of the American Thyroid Association and the Endocrine Society Guidelines
The presence of thyroid autoantibodies is relatively high in women of childbearing age. There is evidence that positive thyroperoxidase antibody even in euthyroid women may increase the risk of spontaneous and recurrent pregnancy loss and preterm delivery. However, the evidence is not enough to just...
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Published in: | Journal of Thyroid Research 2013-01, Vol.2013 (2013), p.106-111 |
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container_end_page | 111 |
container_issue | 2013 |
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container_title | Journal of Thyroid Research |
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creator | Mehran, Ladan Tohidi, M. Sarvghadi, Farzaneh Delshad, Hossein Amouzegar, Atieh Soldin, Offie P. Azizi, Fereidoun |
description | The presence of thyroid autoantibodies is relatively high in women of childbearing age. There is evidence that positive thyroperoxidase antibody even in euthyroid women may increase the risk of spontaneous and recurrent pregnancy loss and preterm delivery. However, the evidence is not enough to justify recommendation on the screening of pregnant women for thyroid autoantibodies or LT4 supplementation for reducing maternal or fetal complications. In this paper we reviewed the related evidence and compared the new guidelines of the American Thyroid Association and Endocrine Society with respect to the screening and management of positive thyroperoxidase antibody in euthyroid pregnant women. As there was no major contradiction or disagreement between the two guidelines, either one of two guidelines may be used by clinicians for the appropriate management of thyroid autoimmunity during pregnancy. |
doi_str_mv | 10.1155/2013/542692 |
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There is evidence that positive thyroperoxidase antibody even in euthyroid women may increase the risk of spontaneous and recurrent pregnancy loss and preterm delivery. However, the evidence is not enough to justify recommendation on the screening of pregnant women for thyroid autoantibodies or LT4 supplementation for reducing maternal or fetal complications. In this paper we reviewed the related evidence and compared the new guidelines of the American Thyroid Association and Endocrine Society with respect to the screening and management of positive thyroperoxidase antibody in euthyroid pregnant women. As there was no major contradiction or disagreement between the two guidelines, either one of two guidelines may be used by clinicians for the appropriate management of thyroid autoimmunity during pregnancy.</description><identifier>ISSN: 2042-0072</identifier><identifier>ISSN: 2090-8067</identifier><identifier>EISSN: 2042-0072</identifier><identifier>DOI: 10.1155/2013/542692</identifier><identifier>PMID: 23738229</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Limiteds</publisher><subject>Age ; Antibodies ; Autoantibodies ; Care and treatment ; Clinical medicine ; Health aspects ; Hypothyroidism ; In vitro fertilization ; Iodine ; Miscarriage ; Pregnancy complications ; Pregnant women ; Review ; Risk factors ; Society ; Thyroid diseases ; Womens health</subject><ispartof>Journal of Thyroid Research, 2013-01, Vol.2013 (2013), p.106-111</ispartof><rights>Copyright © 2013 L. Mehran et al.</rights><rights>COPYRIGHT 2013 John Wiley & Sons, Inc.</rights><rights>Copyright © 2013 L. Mehran et al. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2013 L. Mehran et al. 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a699t-18d415e947c270f3fb9790a26f60753e452f6d66aed94c46c83cfa145e1635093</citedby><cites>FETCH-LOGICAL-a699t-18d415e947c270f3fb9790a26f60753e452f6d66aed94c46c83cfa145e1635093</cites><orcidid>0000-0002-1963-7613</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2407659396/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2407659396?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,25732,27903,27904,36991,36992,44569,53770,53772,74873</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23738229$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Pearce, Elizabeth N.</contributor><contributor>Elizabeth N Pearce</contributor><creatorcontrib>Mehran, Ladan</creatorcontrib><creatorcontrib>Tohidi, M.</creatorcontrib><creatorcontrib>Sarvghadi, Farzaneh</creatorcontrib><creatorcontrib>Delshad, Hossein</creatorcontrib><creatorcontrib>Amouzegar, Atieh</creatorcontrib><creatorcontrib>Soldin, Offie P.</creatorcontrib><creatorcontrib>Azizi, Fereidoun</creatorcontrib><title>Management of Thyroid Peroxidase Antibody Euthyroid Women in Pregnancy: Comparison of the American Thyroid Association and the Endocrine Society Guidelines</title><title>Journal of Thyroid Research</title><addtitle>J Thyroid Res</addtitle><description>The presence of thyroid autoantibodies is relatively high in women of childbearing age. There is evidence that positive thyroperoxidase antibody even in euthyroid women may increase the risk of spontaneous and recurrent pregnancy loss and preterm delivery. However, the evidence is not enough to justify recommendation on the screening of pregnant women for thyroid autoantibodies or LT4 supplementation for reducing maternal or fetal complications. In this paper we reviewed the related evidence and compared the new guidelines of the American Thyroid Association and Endocrine Society with respect to the screening and management of positive thyroperoxidase antibody in euthyroid pregnant women. As there was no major contradiction or disagreement between the two guidelines, either one of two guidelines may be used by clinicians for the appropriate management of thyroid autoimmunity during pregnancy.</description><subject>Age</subject><subject>Antibodies</subject><subject>Autoantibodies</subject><subject>Care and treatment</subject><subject>Clinical medicine</subject><subject>Health aspects</subject><subject>Hypothyroidism</subject><subject>In vitro fertilization</subject><subject>Iodine</subject><subject>Miscarriage</subject><subject>Pregnancy complications</subject><subject>Pregnant women</subject><subject>Review</subject><subject>Risk factors</subject><subject>Society</subject><subject>Thyroid diseases</subject><subject>Womens health</subject><issn>2042-0072</issn><issn>2090-8067</issn><issn>2042-0072</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqFk99r1TAUgIsoblz35LNSEESUu-V3Gx-Ey5hzMHHgxMeQJaf3ZrTJTFr1_i3-s6a3825XBNuHtDnf-dKcnBbFU4wOMeb8iCBMjzgjQpIHxT5BjMwRqsjDe897xUFK1yhfVCKG8ONij9CK1oTI_eLXR-31EjrwfRma8nK1jsHZ8gJi-OmsTlAufO-ugl2XJ0N_G_0aMl86X15EWHrtzfpteRy6Gx1dCn709Kuc2EF0RvutdJFSME73LjPa2w104m0w0XkoP-cY9OvydHAW2jyTnhSPGt0mOLgdZ8WX9yeXxx_m559Oz44X53MtpOznuLYMc5CsMqRCDW2uZCWRJqIRqOIUGCeNsEJosJIZJkxNTaMx44AF5UjSWXE2eW3Q1-omuk7HtQraqc1EiEulY-9MCwplMRUVxxRRhiXUzDLKrakZZ0Dw6Ho3uW6Gqw6syXWNut2R7ka8W6ll-K6oECKfSBa8uhXE8G2A1KvOJQNtqz2EISlMBc8fzfPOZsWLv9DrMESfS6UIQ5XgkkpxRy113oDzTcjrmlGqFrTKGkTyZmbF4T-ofFvonAkeGpfndxJe3ktYgW77VQrtMJ5u2gXfTKCJIaUIzbYYGKmxh9XYw2rq4Uw_v1-_LfunYzPwegJWzlv9w_3H9myCISPQ6C3MaoQ3p3U-xbWLrnd39bvIFo4JogjVGyMm41ChKv9BiOLdF4xEXhvT33vXFCg</recordid><startdate>20130101</startdate><enddate>20130101</enddate><creator>Mehran, Ladan</creator><creator>Tohidi, M.</creator><creator>Sarvghadi, Farzaneh</creator><creator>Delshad, Hossein</creator><creator>Amouzegar, Atieh</creator><creator>Soldin, Offie P.</creator><creator>Azizi, Fereidoun</creator><general>Hindawi Limiteds</general><general>Hindawi Puplishing Corporation</general><general>Hindawi Publishing Corporation</general><general>John Wiley & Sons, Inc</general><general>Hindawi Limited</general><scope>188</scope><scope>ADJCN</scope><scope>AFFIF</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-1963-7613</orcidid></search><sort><creationdate>20130101</creationdate><title>Management of Thyroid Peroxidase Antibody Euthyroid Women in Pregnancy: Comparison of the American Thyroid Association and the Endocrine Society Guidelines</title><author>Mehran, Ladan ; 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subjects | Age Antibodies Autoantibodies Care and treatment Clinical medicine Health aspects Hypothyroidism In vitro fertilization Iodine Miscarriage Pregnancy complications Pregnant women Review Risk factors Society Thyroid diseases Womens health |
title | Management of Thyroid Peroxidase Antibody Euthyroid Women in Pregnancy: Comparison of the American Thyroid Association and the Endocrine Society Guidelines |
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