Neurological and cardiac complications in a cohort of children with end-stage renal disease

• Published in: Saudi journal of kidney diseases and transplantation 2016-05, Vol.27 (3), p.507-511
• Main Authors: al-Barmaki, Jumanah H., al-Ammuri, Iyad A., Aql, Kamal F.
• Format: Article
• Language: English
• Subjects: Adolescent; Cardiovascular diseases; Child; Complications; Complications and side effects; Diseases; Female; Forecasts and trends; Heart Diseases - complications; Heart Diseases - epidemiology; Humans; Kidney diseases; Kidney Failure, Chronic - complications; Kidney Failure, Chronic - epidemiology; Kidneys; Male; Medical statistics; Nervous System Diseases - complications; Nervous System Diseases - epidemiology; Neurologic manifestations; Risk factors; الأطفال; الأمراض; الفشل الكلوي; الكلى; المرضى; المضاعفات; طب الأعصاب
• ISSN: 1319-2442; 2320-3838
• DOI: 10.4103/1319-2442.182384

Adult patients with chronic kidney disease are at risk of major neurologic and cardiac complications. The purpose of this study is to review the neurological and cardiac complications in children with end-stage renal disease (ESRD). A retrospective review of medical records of children with ESRD at Jordan University Hospital was performed. All neurological and cardiac events were recorded and analyzed. Data of a total of 68 children with ESRD presenting between 2002 and 2013 were reviewed. Neurological complications occurred in 32.4%; seizures were the most common event. Uncontrolled hypertension was the leading cause of neurological events. Cardiac complications occurred in 39.7%, the most common being pericardial effusion. Mortality from neurological complications was 45%. Neurological and cardiac complications occurred in around a third of children with ESRD with a high mortality rate. More effective control of hypertension, anemia, and intensive and gentle dialysis are needed.