Recommendations for addressing the translational gap between experimental and clinical research on amyloid diseases

This paper is a report of recommendations for addressing translational challenges in amyloid disease research. They were developed during and following an international online workshop organized by the LINXS Institute of Advanced Neutron and X-Ray Science in March 2021. Key suggestions include impro...

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Bibliographic Details
Published in:Journal of translational medicine 2022-05, Vol.20 (1), p.213-7, Article 213
Main Authors: Solomon, Miriam, Foderà, Vito, Langkilde, Annette Eva, Elliott, Perry, Tagliavini, Fabrizio, Forsyth, Trevor, Klementieva, Oxana, Bellotti, Vittorio
Format: Article
Language:English
Subjects:
Alzheimer's disease
Amyloid
Amyloid diseases
Amyloidosis
Basic Medicine
Biochemistry and Molecular Biology
Biokemi och molekylärbiologi
Biologi
Biological Sciences
Cell and Molecular Biology
Cell- och molekylärbiologi
Clinical trials
Complexity
Heterogeneity
Management
Medical and Health Sciences
Medicin och hälsovetenskap
Medicine
Medicinska och farmaceutiska grundvetenskaper
Meeting Report
Natural Sciences
Naturvetenskap
Negative results
Philosophers
Proteins
Questionnaires
Science
Scientists
Translation
Translational medicine
Translational research
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Summary:This paper is a report of recommendations for addressing translational challenges in amyloid disease research. They were developed during and following an international online workshop organized by the LINXS Institute of Advanced Neutron and X-Ray Science in March 2021. Key suggestions include improving cross-cultural communication between basic science and clinical research, increasing the influence of scientific societies and journals (vis-à-vis funding agencies and pharmaceutical companies), improving the dissemination of negative results, and strengthening the ethos of science.
ISSN:1479-5876
1479-5876
DOI:10.1186/s12967-022-03420-9