Antioxidative and Anti-Inflammatory Properties of Cannabidiol

Cannabidiol (CBD) is one of the main pharmacologically active phytocannabinoids of L. CBD is non-psychoactive but exerts a number of beneficial pharmacological effects, including anti-inflammatory and antioxidant properties. The chemistry and pharmacology of CBD, as well as various molecular targets...

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Bibliographic Details
Published in:Antioxidants 2019-12, Vol.9 (1), p.21
Main Authors: Atalay, Sinemyiz, Jarocka-Karpowicz, Iwona, Skrzydlewska, Elzbieta
Format: Article
Language:English
Subjects:
Amino acids
Anti-inflammatory agents
Antioxidants
Biological activity
Cannabidiol
cannabidiol synthetic derivatives
Cannabinoid receptors
Cannabinoids
Cannabis
Cardiomyopathy
Diabetes
Diabetic neuropathy
Drug therapy
Endocannabinoid system
endocannabinoids
Enzymes
Free radicals
Inflammation
lipid peroxidation
membrane receptors
Molecular weight
Oxidation
Oxidative stress
Proteins
Review
Tetrahydrocannabinol
THC
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Summary:Cannabidiol (CBD) is one of the main pharmacologically active phytocannabinoids of L. CBD is non-psychoactive but exerts a number of beneficial pharmacological effects, including anti-inflammatory and antioxidant properties. The chemistry and pharmacology of CBD, as well as various molecular targets, including cannabinoid receptors and other components of the endocannabinoid system with which it interacts, have been extensively studied. In addition, preclinical and clinical studies have contributed to our understanding of the therapeutic potential of CBD for many diseases, including diseases associated with oxidative stress. Here, we review the main biological effects of CBD, and its synthetic derivatives, focusing on the cellular, antioxidant, and anti-inflammatory properties of CBD.
ISSN:2076-3921
2076-3921
DOI:10.3390/antiox9010021